Evidence map›Paper›PMID 32881377›Full record

ArticleCancer medicine2020

Health-related quality of life of patients with multiple myeloma: A real-world study in China.

Xiaozhe Li, Junru Liu, Meilan Chen, Jingli Gu, Beihui Huang, Dong Zheng, Juan Li

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Quality of Life Among Polish Patients with Multiple Myeloma: A Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Myélome multiple et approche palliative des soins : étude théorique ancrée dans la pratique.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024
    Article
  10. Article
  11. The experiences of living with multiple myeloma and a palliative approach to care: A grounded theory study.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024
    Article
  12. Assessment tools for patient-reported outcomes in multiple myeloma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Review
  13. Real-world patient-reported outcomes and concordance between patient and physician reporting of side effects across lines of therapy in multiple myeloma within the USA.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaozhe LiDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Junru LiuDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Meilan ChenDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jingli GuDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Beihui HuangDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-2804-4913
Dong ZhengDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Juan LiDepartment of Haematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-0909-4731
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to assess the health-related quality of life (HRQOL) of Chinese patients with different stages of multiple myeloma (MM) who received various treatments and identify the factors associated with a lower quality of life in China.

methodsA cross-sectional, anonymous questionnaire was distributed to adults with MM. The measures of quality of life included the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-C30, QLQ-myeloma-specific module 20 (MY20), and EuroQoL EQ-5D. The data, including patient factors, difficulties experienced during the diagnosis and treatment processes, psychosocial factors and disease- or treatment-related effects, were collected.

resultsFour hundred and thirty patients with MM were recruited from all 27 provinces of China, and their average age was 55.7 years. Many variables were significantly associated with the HRQOL of the patients with MM. In the multivariate analyses, performance status, psychosocial factors, disease phase, and an early diagnosis were significantly associated with the HRQOL. In the subgroup analysis, the HRQOL of the patients who underwent autologous stem cell transplantation (ASCT) was significantly higher than that of the non-ASCT patients. Treatment-related toxicities had a significant impact on the quality of life of the patients with MM, and 91.5% of the patients intended to stop the maintenance treatment.

conclusionsThe quality of life of patients with MM in China is affected by patient factors, difficulties experienced during the diagnosis and treatment processes, psychosocial factors, and disease- or treatment-related effects. Efforts should be exerted to improve the overall quality of life of these patients in China.

Indexed as

Quality of LifeStem Cell TransplantationAdultAgedAged, 80 and overAntineoplastic AgentsChinaCross-Sectional StudiesFemaleHealth Care SurveysHumansMaleMiddle AgedMultiple MyelomaNeoplasm StagingRisk AssessmentAntineoplastic Agentshealth-related quality of lifemultiple myeloma

Identifiers

PMID32881377
PMCPMC7643654
OpenAlexW3082176349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.