Evidence map›Paper›PMID 32880791›Full record

ReviewCellular and molecular neurobiology2022

Association Between Pathophysiological Mechanisms of Diabetic Retinopathy and Parkinson's Disease.

Zhuoqing Zhang, Yikun Zhou, Haiyan Zhao, Jinghui Xu, Xiaochun Yang

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Dopamine: A New Player in the Pathogenesis of Diabetic Retinopathy?International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Annals of nuclear medicine · 2023
    Article
  7. Chronobiology of Parkinson's disease: Past, present and future.The European journal of neuroscience · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhuoqing Zhang *Department of Ophthalmology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Yikun Zhou *Department of Endocrinology, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Haiyan Zhao *Department of Ophthalmology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Jinghui XuDepartment of Ophthalmology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Xiaochun YangDepartment of Ophthalmology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. yangxiaochunkm@126.com.ORCID http://orcid.org/0000-0002-0057-0922
Kunming University of Science and Technology · CNFirst People's Hospital of Yunnan Province · CN

Funding

National Natural Science Foundation of China 81660146National Natural Science Foundation of China 81660166Yunnan Science and Technology Talents and Platform Plan 2019HB050Yunnan Youth Talent Support Program YNWR-QNBJ-2018-315
6 · The paper itself

Abstract

Diabetic retinopathy, the most common complication of diabetes, is a neurodegenerative disease in the eye. And Parkinson's disease, affecting the health of 1-2% of people over 60 years old throughout the world, is the second largest neurodegenerative disease in the brain. As the understanding of diabetic retinopathy and Parkinson's disease deepens, the two diseases are found to show correlation in incidence, similarity in clinical presentation, and close association in pathophysiological mechanisms. To reveal the association between pathophysiological mechanisms of the two disease, in this review, the shared pathophysiological factors of diabetic retinopathy and Parkinson's disease are summarized and classified into dopaminergic system, circadian rhythm, neurotrophic factors, α-synuclein, and Wnt signaling pathways. Furthermore, similar and different mechanisms so far as the shared pathophysiological factors of the two disorders are discussed systematically. Finally, a brief summary and new perspectives are presented to provide new directions for further efforts on the association, exploration, and clinical prevention and treatment of diabetic retinopathy and Parkinson's disease.

Indexed as

Diabetes MellitusDiabetic RetinopathyNeurodegenerative DiseasesParkinson Diseasealpha-SynucleinBrainDopamineHumansMiddle Agedalpha-SynucleinDopamineCircadian rhythmDiabetic retinopathyDopamineNeurotrophic factorsParkinson's diseaseWnt signaling pathways

Identifiers

PMID32880791
PMCPMC11441199
OpenAlexW3083215323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.