Evidence map›Paper›PMID 32880432›Full record

ArticleAnalytical chemistry2020

Cell-Type-Specific Metabolic Profiling Achieved by Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Immunofluorescence Staining.

Xin Yan, Xiaoai Zhao, Zhenpeng Zhou, Andrew McKay, Anne Brunet, Richard N Zare

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  7. Review of methods for the determination of cellular cholesterol content: principles, advantages, limitations, applications, and perspectives.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Opto-Lipidomics of Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  12. Emerging Computational Methods in Mass Spectrometry Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  13. Article
  14. Article
  15. Article
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  17. Review
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  19. Review
  20. Introducing Nafion forFrontiers in chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xin YanDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Xiaoai ZhaoDepartment of Genetics, Stanford University, Stanford, California 94305, United States.
Zhenpeng ZhouDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.
Andrew McKayDepartment of Genetics, Stanford University, Stanford, California 94305, United States.
Anne BrunetDepartment of Genetics, Stanford University, Stanford, California 94305, United States.
Richard N ZareDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.ORCID 0000-0001-5266-4253
Stanford University · USTexas A&M University · US

Funding

Wnt signaling in muscle stem cell agingP01AG036695 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMAS A. RANDO · 2011 to 2026
$29.3M
Proteostasis in the aging brainR01AG056290 · NIA · STANFORD UNIVERSITY · PI BRUNET, ANNE, FRYDMAN, JUDITH · 2017 to 2021
$3.2M
NIA NIH HHS P01 AG036695NIA NIH HHS R01 AG056290
6 · The paper itself

Abstract

Cell-type-specific metabolic profiling in tissue with heterogeneous composition has been of great interest across all mass spectrometry imaging (MSI) technologies. We report here a powerful new chemical imaging capability in desorption electrospray ionization (DESI) MSI, which enables cell-type-specific and

Indexed as

Fluorescent Antibody TechniqueAnimalsAstrocytesMachine LearningMiceNeuronsProsencephalonSpectrometry, Mass, Electrospray IonizationSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStaining and Labeling

Identifiers

PMID32880432
PMCPMC8782277
OpenAlexW3083075814

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.