Evidence map›Paper›PMID 32880014›Full record

ArticleSurgical endoscopy2021

Utilizing functional lumen imaging probe in directing treatment for post-fundoplication dysphagia.

Salih Samo, Ramzi Mulki, Marie L Godiers, Chuma G Obineme, Lucie F Calderon, John M Bloch, Joyce J Kim, Nikrad Shahnavaz, Shreya M Raja, Srikrishna V Patnana and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Future perspectives in esophageal manometry.World journal of gastrointestinal surgery · 2025
    Review
  2. Esophageal motility disorders other than achalasia.Abdominal radiology (New York) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Salih SamoDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Ramzi MulkiDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Marie L GodiersDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Chuma G ObinemeDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Lucie F CalderonDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
John M BlochDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Joyce J KimDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Nikrad ShahnavazDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Shreya M RajaAtlanta VA Medical Center and Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, USA.
Srikrishna V PatnanaDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Field F WillinghamDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Steven A KeilinDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Qiang CaiDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Jennifer A ChristieDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Shanthi SrinivasanDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA.
Edward LinDivision of Foregut Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, USA.
S Scott DavisDivision of Foregut Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, USA.
Anand S JainDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 1525 Clifton Rd NE, Atlanta, GA, 30322, USA. anand.jain@emory.edu.ORCID http://orcid.org/0000-0002-7097-0446
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophagogastric junction obstruction (EGJO) post-fundoplication (PF) is difficult to identify with currently available tests. We aimed to assess the diagnostic accuracy of EGJ opening on functional lumen imaging probe (FLIP) and dilation outcome in FLIP-detected EGJO in PF dysphagia.

methodsWe prospectively collected data on PF patients referred to Esophageal Clinic over 18 months. EGJO diagnosis was made by (a) endoscopist's description of a narrow EGJ/wrap area, (b) appearance of wrap obstruction or contrast/tablet retention on esophagram, or (c) EGJ-distensibility index (DI) < 2.8 mm

resultsTwenty-six patients were included, of whom 17 (65%) had a low EGJ-DI. No patients had a hiatal hernia greater than 3 cm. Dysphagia was the primary symptom in 17/26 (65%). In 85% (κ = 0.677) of cases, EGJ assessment (tight vs. open) was congruent between the combination of endoscopy (n = 26) and esophagram (n = 21) vs. EGJ-DI (n = 26) on FLIP. Follow-up data were available in 11 patients who had dilation based on a low EGJ-DI (4 with 20 mm balloon and 7 with ≥ 30 mm balloon). Overall, the mean % improvement in dysphagia was 60% (95% CI 37.7-82.3%, p = 0.0001). Nine out of 11 patients, including 6 out of 7 undergoing pneumatic dilation, had improvement ≥ 50% in dysphagia (mean % improvement 72.2%; 95% CI 56.1-88.4%, p = 0.0001). CONCLUSIONS AND INFERENCES: Functional lumen imaging probe is an accurate modality for evaluating for EGJ obstruction PF. FLIP may be used to select patients who may benefit from larger diameter dilation.

Indexed as

Deglutition DisordersEsophageal AchalasiaEsophagogastric JunctionFundoplicationHumansManometryDilationDysphagiaFunctional lumen imaging probeFundoplicationPneumatic dilation

Identifiers

PMID32880014
OpenAlexW3082075603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.