ArticleNature catalysis2019
α-Branched amines by catalytic 1,1-addition of C-H bonds and aminating agents to terminal alkenes.
Article in Nature catalysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 126 citations in OpenAlex.
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- DigiChemTree enables programmable light-induced carbene generation for on demand chemical synthesis.Communications chemistry · 2024Article
- Late-stage synthesis of heterobifunctional molecules for PROTAC applications via ruthenium-catalysed C‒H amidation.Nature communications · 2023Article
- Catalytic, asymmetric carbon-nitrogen bond formation using metal nitrenoids: from metal-ligand complexesChemical science · 2023Review
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- Nickel-Catalyzed 1,1-Aminoborylation of Unactivated Terminal Alkenes.ACS catalysis · 2023Article
- Modular Synthesis of Unnatural Peptides via Rh(III)-Catalyzed Diastereoselective Three-Component Carboamidation Reaction.Journal of the American Chemical Society · 2023Article
- Rhodium-catalyzed enantioselective C-H alkynylation of sulfoxides in diverse patterns: desymmetrization, kinetic resolution, and parallel kinetic resolution.Chemical science · 2023Article
- Rhodium(III)-Catalyzed Anti-Markovnikov Hydroamidation of Unactivated Alkenes Using Dioxazolones as Amidating Reagents.Journal of the American Chemical Society · 2022Article
- C-H bond activation and sequential addition to two different coupling partners: a versatile approach to molecular complexity.Chemical Society reviews · 2022Review
- Stereoselective Synthesis of Allenyl Alcohols by Cobalt(III)-Catalyzed Sequential C-H Bond Addition to 1,3-Enynes and Aldehydes.Angewandte Chemie (International ed. in English) · 2022Article
- α-Branched amines through radical coupling with 2-azaallyl anions, redox active esters and alkenes.Chemical science · 2022Article
- Rh(III)-Catalyzed Three-ComponentACS catalysis · 2021Article
- Three-Component 1,2-Carboamidation of Bridged Bicyclic Alkenes via RhOrganic letters · 2021Article
- Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions.Chemical science · 2021Article
- Synthesis of Nitrile Bearing Acyclic Quaternary Centers through Co(III)-Catalyzed Sequential C-H Bond Addition to Dienes and N-Cyanosuccinimide.Angewandte Chemie (International ed. in English) · 2021Article
- Rh(iii)-catalyzed tandem annulative redox-neutral arylation/amidation of aromatic tethered alkenes.Chemical science · 2020Article
- Walking metals: catalytic difunctionalization of alkenes at nonclassical sites.Chemical science · 2020Review
- Cobalt(III)-Catalyzed Diastereoselective Three-Component C-H Bond Addition to Butadiene and Activated Ketones.Synthesis · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
α-Branched amines are present in hundreds of pharmaceutical agents and clinical candidates and are important targets for synthesis. Here we show the convergent synthesis of α-branched amines from three readily accessible starting materials: aromatic C-H bond substrates, terminal alkenes, and aminating agents. This reaction proceeds by an intermolecular formation of C-C and C-N bonds at the
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.