Evidence map›Paper›PMID 32879854›Full record

ArticleQuantitative imaging in medicine and surgery2020

Diagnostic interchangeability of deep convolutional neural networks reconstructed knee MR images: preliminary experience.

Naveen Subhas, Hongyu Li, Mingrui Yang, Carl S Winalski, Joshua Polster, Nancy Obuchowski, Kenji Mamoto, Ruiying Liu, Chaoyi Zhang, Peizhou Huang and 5 more

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  7. A miniature U-net forQuantitative imaging in medicine and surgery · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Naveen SubhasProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Hongyu LiDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.
Mingrui YangProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Carl S WinalskiProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Joshua PolsterProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Nancy ObuchowskiProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Kenji MamotoProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Ruiying LiuDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.
Chaoyi ZhangDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.
Peizhou HuangDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.
Sunil Kumar GaireDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.
Dong LiangPaul C. Lauterbur Research Center for Biomedical Imaging, Medical AI Research Center, SIAT, CAS, Shenzhen, China.
Bowen ShenDepartment of Computer Science, Virginia Tech, Blacksburg, VA, USA.
Xiaojuan LiProgram of Advanced Musculoskeletal Imaging (PAMI), Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Leslie YingDepartment of Biomedical Engineering, Department of Electrical Engineering, University at Buffalo, the State University of New York, Buffalo, NY, USA.

Funding

Kernel-based Nonlinear Learning for Fast Magnetic Resonance Imaging with Sub-Nyquist SamplingR21EB020861 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI YING, LESLIE LEI · 2015 to 2016
$403k
NIBIB NIH HHS R21 EB020861
6 · The paper itself

Abstract

backgroundMRI acceleration using deep learning (DL) convolutional neural networks (CNNs) is a novel technique with great promise. Increasing the number of convolutional layers may allow for more accurate image reconstruction. Studies on evaluating the diagnostic interchangeability of DL reconstructed knee magnetic resonance (MR) images are scarce. The purpose of this study was to develop a deep CNN (DCNN) with an optimal number of layers for accelerating knee magnetic resonance imaging (MRI) acquisition by 6-fold and to test the diagnostic interchangeability and image quality of nonaccelerated images versus images reconstructed with a 15-layer DCNN or 3-layer CNN.

methodsFor the feasibility portion of this study, 10 patients were randomly selected from the Osteoarthritis Initiative (OAI) cohort. For the interchangeability portion of the study, 40 patients were randomly selected from the OAI cohort. Three readers assessed meniscal and anterior cruciate ligament (ACL) tears and cartilage defects using DCNN, CNN, and nonaccelerated images. Image quality was subjectively graded as nondiagnostic, poor, acceptable, or excellent. Interchangeability was tested by comparing the frequency of agreement when readers used both accelerated and nonaccelerated images to frequency of agreement when readers only used nonaccelerated images. A noninferiority margin of 0.10 was used to ensure type I error ≤5% and power ≥80%. A logistic regression model using generalized estimating equations was used to compare proportions; 95% confidence intervals (CIs) were constructed.

resultsDCNN and CNN images were interchangeable with nonaccelerated images for all structures, with excess disagreement values ranging from -2.5% [95% CI: (-6.1, 1.1)] to 3.0% [95% CI: (-0.1, 6.1)]. The quality of DCNN images was graded higher than that of CNN images but less than that of nonaccelerated images [excellent/acceptable quality: DCNN, 95% of cases (114/120); CNN, 60% (72/120); nonaccelerated, 97.5% (117/120)].

conclusionsSix-fold accelerated knee images reconstructed with a DL technique are diagnostically interchangeable with nonaccelerated images and have acceptable image quality when using a 15-layer CNN.

Indexed as

artificial intelligenceDeep learning (DL)knee MRIMRI acceleration technique

Identifiers

PMID32879854
PMCPMC7417759

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.