Evidence map›Paper›PMID 32879782›Full record

ArticleTranslational vision science & technology2020

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone-Rod Dystrophy.

Jason C Park, Frederick T Collison, Gerald A Fishman, J Jason McAnany

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jason C ParkDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Frederick T CollisonThe Pangere Center for Inherited Retinal Diseases, The Chicago Lighthouse, Chicago, IL, USA.
Gerald A FishmanDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
J Jason McAnanyDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
University of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
NEI NIH HHS P30 EY001792
6 · The paper itself

Abstract

Purpose: To compare electrophysiological and pupillometric responses in subjects with cone-rod dystrophy due to autosomal recessive (AR) Methods: Four subjects with AR Results: Light-adapted ERGs were non-detectable in all four Conclusions: ERG and PLR comparison showed an unanticipated dichotomy: ERGs were generally non-detectable, whereas PLRs were normal for all Translational Relevance: These data highlight the potential usefulness of pupillometry in cases where the ERG is non-detectable.

Indexed as

Cone-Rod DystrophiesAC133 AntigenDark AdaptationElectroretinographyHumansPhotic StimulationRetinal Cone Photoreceptor CellsAC133 AntigenPROM1 protein, humancone–rod dystrophyelectrophysiologyPROM1pupillometry

Identifiers

PMID32879782
PMCPMC7442873
OpenAlexW3059758076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.