Evidence map›Paper›PMID 32879768›Full record

ArticleTranslational vision science & technology2020

Detection of Functional Deterioration in Glaucoma by Trend Analysis Using Overlapping Clusters of Locations.

Stuart K Gardiner, Steven L Mansberger

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stuart K GardinerDevers Eye Institute, Legacy Research Institute, Portland, OR, USA.
Steven L MansbergerDevers Eye Institute, Legacy Research Institute, Portland, OR, USA.
Legacy Health · US

Funding

Functional Testing for GlaucomaR01EY020922 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI GARDINER, STUART · 2011 to 2021
$3.2M
NEI NIH HHS R01 EY020922
6 · The paper itself

Abstract

Purpose: Cluster trend analysis detects glaucomatous deterioration within predefined subsets (clusters) of visual field locations. However, it may miss small defects straddling boundaries between the clusters. This study assesses whether simultaneously using a second set of clusters, overlapping the first, could improve progression detection. Methods: Deterioration in eyes with or at risk of glaucomatous visual field loss was "detected" by mean deviation (MD) on the first visit at which the Results: Biannual series of ≥5 visual fields (mean = 14) were available for 420 eyes of 213 participants. Deterioration of 33% of eyes was detected earliest using Conclusions: After equalizing specificity, overlapping clusters of locations did not significantly reduce the time to detect deterioration compared with nonoverlapping clusters. Translational Relevance: Cluster trend analyses detected deterioration sooner than global analyses even when defects straddled cluster borders.

Indexed as

GlaucomaTetrahymeninaHumansVision DisordersVisual FieldsVisual Field Testsdata analysisglaucomaperimetryprogression

Identifiers

PMID32879768
PMCPMC7442868
OpenAlexW3047085079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.