Evidence map›Paper›PMID 32879722›Full record

ReviewFrontline gastroenterology2020

Adult liver transplantation: UK clinical guideline - part 2: surgery and post-operation.

Charles Millson, Aisling Considine, Matthew E Cramp, Andrew Holt, Stefan Hubscher, John Hutchinson, Kate Jones, Joanna Leithead, Steven Masson, Krish Menon and 10 more

Open access · hybridAbstract readReview
In one paragraph

Review in Frontline gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Effects ofBiomedicines · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. A Conceptual Framework for Evaluating National Organ Donation and Transplantation Programs.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 1 country.

Charles MillsonDepartment of Hepatology, York Teaching Hospitals NHS Foundation Trust, York, UK.ORCID 0000-0001-6989-9497
Aisling ConsidinePharmacy department, King's College Hospital NHS Foundation Trust, London, UK.
Matthew E CrampSouth West Liver Unit, Plymouth Hospitals NHS Trust, Plymouth, UK.
Andrew HoltLiver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Stefan HubscherDepartment of Cellular Pathology, University of Birmingham, Birmingham, UK.
John HutchinsonDepartment of Hepatology, York Teaching Hospitals NHS Foundation Trust, York, UK.
Kate JonesLiver Transplantation Service, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Joanna LeitheadDepartment of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Steven MassonLiver Unit, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Krish MenonLiver Transplantation & HPB Surgery, King's College Hospital NHS Foundation Trust, London, UK.
Darius MirzaLiver Transplantation & HPB surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
James NeubergerLiver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Raj PrasadLiver Transplantation & HPB Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Anthony PrattPharmacy Department, York Teaching Hospital NHS Foundation Trust, York, UK.
Wendy PrenticePalliative Care Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Liz ShepherdLiver Transplantation Service, Royal Free London NHS Foundation Trust, London, UK.
Ken SimpsonScottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Doug ThorburnDepartment of Hepatology, Royal Free London NHS Foundation Trust, London, UK.
Rachel WestbrookDepartment of Hepatology, Royal Free London NHS Foundation Trust, London, UK.
Dhiraj TripathiLiver Unit, University Hospitals Birmingham NHS Foundation Trust, Birminghams, UK.
University Hospitals Birmingham NHS Foundation Trust · GBKing's College Hospital NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBLeeds Teaching Hospitals NHS Trust · GBYork Teaching Hospital NHS Foundation Trust · GBCambridge University Hospitals NHS Foundation Trust · GBEdinburgh Royal Infirmary · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBPlymouth Hospital · GBUniversity of Birmingham · GBYork Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survival rates for patients following liver transplantation exceed 90% at 12 months and approach 70% at 10 years. Part 1 of this guideline has dealt with all aspects of liver transplantation up to the point of placement on the waiting list. Part 2 explains the organ allocation process, organ donation and organ type and how this influences the choice of recipient. After organ allocation, the transplant surgery and the critical early post-operative period are, of necessity, confined to the liver transplant unit. However, patients will eventually return to their referring secondary care centre with a requirement for ongoing supervision. Part 2 of this guideline concerns three key areas of post liver transplantation care for the non-transplant specialist: (1) overseeing immunosuppression, including interactions and adherence; (2) the transplanted organ and how to initiate investigation of organ dysfunction; and (3) careful oversight of other organ systems, including optimising renal function, cardiovascular health and the psychosocial impact. The crucial significance of this holistic approach becomes more obvious as time passes from the transplant, when patients should expect the responsibility for managing the increasing number of non-liver consequences to lie with primary and secondary care.

Indexed as

guidelineliver transplantation

Identifiers

PMID32879722
PMCPMC7447281
OpenAlexW3008395351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.