Evidence map›Paper›PMID 32879592›Full record

ArticleAnnals of gastroenterology

Gastrointestinal involvement in COVID-19 patients: a retrospective study from a Greek COVID-19 referral hospital.

Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Alexandra Agorogianni, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Review
  8. Reply.Gastroenterology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Panagiotis TsibourisDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Konstantinos EkmektzoglouDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Alexandra Agorogianni2 Department of Internal Medicine, Army Share Fund Hospital (NIMTS), Athens, Greece (Alexandra Agorogianni).
Chrysostomos KalantzisDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Antonia TheofanopoulouDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Klearchos ToumbelisDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Leonidas PetrogiannopoulosDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Charalambos PoutakidisDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Stavroula GoggakiDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Ioannis BraimakisDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Erasmia VlachouDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
Abraham Pouliakis2 Department of Pathology, "ATTIKON" University Hospital, National and Kapodistrian University of Athens, Athens, Greece (Abraham Pouliakis).
Periklis ApostolopoulosDepartment of Gastroenterology, Army Share Fund Hospital (NIMTS), Athens, Greece (Panagiotis Tsibouris, Konstantinos Ekmektzoglou, Chrysostomos Kalantzis, Antonia Theofanopoulou, Klearchos Toumbelis, Leonidas Petrogiannopoulos, Charalambos Poutakidis, Stavroula Goggaki, Ioannis Braimakis, Erasmia Vlachou, Periklis Apostolopoulos).
NIMTS Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMuch attention has been paid to the study and reporting of gastrointestinal (GI) symptoms in COVID-19 patients. Moreover, an increasing number of COVID-19 patients have been noted to experience hepatic and pancreatic injury. In this study, we retrospectively investigated symptoms and laboratory findings related to the GI system in a single center in Athens, Greece, and assessed the role of these parameters in relation to survival and disease severity.

methodWe retrospectively studied 61 adult COVID-19 patients admitted to the Army Share Fund Hospital (NIMTS) in Athens, Greece, from April 6th to May 6

resultsSixty-one COVID-19 cases were assessed in the study period. Regarding both survival and disease severity, diarrhea was the most common finding. The multivariate analysis revealed that elevated serum aspartate aminotransferase levels and low serum albumin levels were associated with worse patient survival (odds ratio [OR] 1.029, 95% confidence interval [CI] 1.007-1.05, P=0.0088; and OR 0.219, 95%CI 0.066-0.723, P=0.0127, respectively). As far as disease severity is concerned, only a low serum albumin level (measured at hospital admission) was correlated with more severe disease (OR 0.025, 95%CI 0.004-0.161, P=0.0001).

conclusionsOutpatients with new-onset GI symptoms should be considered for COVID-19 testing in a high COVID-19 prevalence setting, as these symptoms are observed more and more in clinical settings. As prospective studies begin to emerge, clinicians will have more robust research data to diagnose COVID-19 patients earlier and identify patients in need of more intensive treatment.

Indexed as

COVID-19gastrointestinal symptomsGreeceretrospectiveSARS-CoV-2

Identifiers

PMID32879592
PMCPMC7406807
OpenAlexW3038451196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.