ArticleBiology of sport2020
Whole genome sequencing of elite athletes.
Article in Biology of sport, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Pooled it
- Effect ofNutrients · 2024Trial
- EPAS1 is associated with human muscle fiber composition and endurance phenotypes.Physiological reports · 2026Article
- Integrating machine learning and GWAS for variant prioritization in the INCIPE cohort highlights ABC transporter genes in chronic kidney disease.Frontiers in genetics · 2026Article
- Association analysis of indel variants and gene expression identifies MDM4 as a novel locus for skeletal muscle hypertrophy and power athlete status.Experimental physiology · 2025Article
- Effects of Exercise Addiction and theGenes · 2025Article
- BDNF coexpresses with MTOR and is associated with muscle fiber size, lean mass and power-related traits.European journal of applied physiology · 2025Article
- TheGenes · 2025Article
- Air Pollution and Its Impact on Health and Performance in Football Players.Sports (Basel, Switzerland) · 2025Review
- Association Between Genetically Predicted Memory and Self-Reported Foreign Language Proficiency.Genes · 2025Article
- Injury Prevention Strategies in Female Football Players: Addressing Sex-Specific Risks.Sports (Basel, Switzerland) · 2025Review
- Genome-Wide Association Study of Exercise Addiction Among Elite Wrestlers.Brain sciences · 2025Article
- TheMetabolites · 2024Article
- Genetic Determinants of Endurance: A Narrative Review on Elite Athlete Status and Performance.International journal of molecular sciences · 2024Review
- Genomic Insights into Idiopathic Granulomatous Mastitis through Whole-Exome Sequencing: A Case Report of Eight Patients.International journal of molecular sciences · 2024Article
- Whole-Exome Sequencing and Experimental Validation Unveil the Roles of TMEM229A Q200del Mutation in Lung Adenocarcinoma.The clinical respiratory journal · 2024Article
- Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers.BMC sports science, medicine & rehabilitation · 2024Article
- Genes and Athletic Performance: The 2023 Update.Genes · 2023Review
- Article
- Association analysis of 10 candidate genes causing Mendelian calcium nephrolithiasis in the INCIPE study: a South European general population cohort.Clinical kidney journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whole genome sequencing (WGS) has great potential to explore all possible DNA variants associated with physical performance, psychological traits and health conditions of athletes. Here we present, for the first time, annotation of genomic variants of elite athletes, based on the WGS of 20 Tatar male wrestlers. The maximum number of high-quality variants per sample was over 3.8 M for single nucleotide polymorphisms (SNPs) and about 0.64 M for indels. The maximum number of nonsense mutations was 148 single nucleotide variants (SNVs) per individual. Athletes' genomes on average contained 18.9 nonsense SNPs in a homozygous state per sample, while non-athletes' exomes (Tatar controls, n = 19) contained 18 nonsense SNPs. Finally, we applied genomic data for the association analysis and used reaction time (RT) as an example. Out of 1884 known genome-wide significant SNPs related to RT, we identified four SNPs (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.