ReviewNature reviews. Clinical oncology2020
Older adults with cancer and their caregivers - current landscape and future directions for clinical care.
Review in Nature reviews. Clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors related to good death from the perspectives of informal caregivers of cancer patients: a systematic review.BMC palliative care · 2025Pooled it
- Clinical Outcomes and Prognostic Implications of TAVR in Patients With Active Cancer: A Meta-Analysis.Clinical cardiology · 2025Pooled it
- The shared uncertainty experience of older adults with advanced cancer and their caregivers.Psycho-oncology · 2022Trial
- Quality cancer care for older adults in rural settings: Perspectives from the Cancer and Aging Research Group Junior Board.Journal of geriatric oncology · 2026Article
- Considering the caregiver in early-phase clinical trials: a review of trial protocols and consent forms.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Review
- Quality of life dynamics in the gastric cancer dyad: an actor-partner interdependence model analysis guiding the development of a family-centered nursing framework.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026Review
- The Experience of Depression in Older Adults With Cancer: A Qualitative Descriptive Analysis.Psycho-oncology · 2026Article
- The Mediating Role of Inner Strength in the Relationship Between Illness Perception and Self-Management in Older Adults with Advanced Lung Cancer: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Dietary restriction mitigates 5-fluorouracil-induced thrombocytopenia in aged mice via mitochondrial potentiation in hematopoietic stem cells and megakaryocyte progenitors.Stem cell reports · 2026Article
- Tumor biology, treatment patterns, and recurrence in breast cancer patients aged 70-79 vs ≥ 80 years: a large-scale registry analysis.Archives of gynecology and obstetrics · 2026Article
- Prehabilitation in Adult Cancer Patients Undergoing Chemotherapy or Radiotherapy: A Scoping Review.Cancers · 2026Review
- Aging modulation of the immune system and immunotherapy efficacy in cancer.Frontiers in immunology · 2026Review
- Functional Stratification and Long-Term Care Service Patterns among Discharged Patients with Cancer: A Retrospective Study from Taiwan.Journal of Cancer · 2026Article
- Socioeconomic Disparities in Caregiver Burden Among Families of Older Patients With Cancer.JAMA health forum · 2025Article
- Chain-mediating effect of illness acceptance and perceived control on the relationship between family caring and self-perceived burden in elderly patients with breast cancer: a cross-sectional study.Journal of cancer survivorship : research and practice · 2025Article
- Cancer treatments accelerate ageing.Nature reviews. Cancer · 2025Article
- Adaptation and Implementation of Self-System Therapy for Older Adults with Advanced Lung Cancer: Pilot Trial Results.Cancers · 2025Article
- Exploring Determinants of Compassionate Cancer Care in Older Adults Using Fuzzy Cognitive Mapping.Current oncology (Toronto, Ont.) · 2025Article
- Exploring factors affecting the adoption and use of digital health technologies among older adults with cancer: A qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Despite substantial improvements in the outcomes of patients with cancer over the past two decades, older adults (aged ≥65 years) with cancer are a rapidly increasing population and continue to have worse outcomes than their younger counterparts. Managing cancer in this population can be challenging because of competing health and ageing-related conditions that can influence treatment decision-making and affect outcomes. Geriatric screening tools and comprehensive geriatric assessment can help to identify patients who are most at risk of poor outcomes from cancer treatment and to better allocate treatment for these patients. The use of evidence-based management strategies to optimize geriatric conditions can improve communication and satisfaction between physicians, patients and caregivers as well as clinical outcomes in this population. Clinical trials are currently underway to further determine the effect of geriatric assessment combined with management interventions on cancer outcomes as well as the predictive value of geriatric assessment in the context of treatment with contemporary systemic therapies such as immunotherapies and targeted therapies. In this Review, we summarize the unique challenges of treating older adults with cancer and describe the current guidelines as well as investigational studies underway to improve the outcomes of these patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.