Evidence map›Paper›PMID 32879419›Full record

ArticleScientific reports2020

VEGF-A splice variants bind VEGFRs with differential affinities.

Spencer B Mamer, Ashley Wittenkeller, P I Imoukhuede

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Polymorphisms inBiomedicines · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
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  18. A method for rapid and reliable quantification of VEGF-cell binding activity.Biochemical and biophysical research communications · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Spencer B MamerDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA. smamer2@illinois.edu.ORCID http://orcid.org/0000-0002-5613-3596
Ashley WittenkellerDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
P I ImoukhuedeDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
University of Illinois Urbana-Champaign · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial growth factor A (VEGF-A) and its binding to VEGFRs is an important angiogenesis regulator, especially the earliest-known isoform, VEGF-A

Indexed as

Alternative SplicingHumansNeovascularization, PhysiologicProtein BindingProtein IsoformsReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AProtein IsoformsReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID32879419
PMCPMC7468149
OpenAlexW3082734498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.