Evidence map›Paper›PMID 32879395›Full record

ArticleScientific reports2020

Mass mortality in freshwater mussels (Actinonaias pectorosa) in the Clinch River, USA, linked to a novel densovirus.

Jordan C Richard, Eric Leis, Christopher D Dunn, Rose Agbalog, Diane Waller, Susan Knowles, Joel Putnam, Tony L Goldberg

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 64 citations in OpenAlex.

  1. Distribution, scale, and drivers of mass mortality events in Europe's freshwater bivalves.Conservation biology : the journal of the Society for Conservation Biology · 2026
    Article
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  5. Article
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  7. Parvoviruses of Aquatic Animals.Pathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Article
  10. Viral Diversity in Samples of Freshwater GastropodsInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
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  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jordan C RichardU.S. Fish and Wildlife Service, Southwestern Virginia Field Office, 330 Cummings Street, Abingdon, VA, 24210, USA.
Eric LeisLa Crosse Fish Health Center, Midwest Fisheries Center, U.S. Fish and Wildlife Service, 555 Lester Ave, Onalaska, WI, 54650, USA.
Christopher D DunnDepartment of Pathobiological Sciences and Freshwater and Marine Sciences Program, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI, 53706, USA.
Rose AgbalogU.S. Fish and Wildlife Service, Southwestern Virginia Field Office, 330 Cummings Street, Abingdon, VA, 24210, USA.
Diane WallerU.S. Geological Survey, Upper Midwest Environmental Sciences Center, 2630 Fanta Reed Rd, La Crosse, WI, 54603, USA.
Susan KnowlesU.S. Geological Survey, National Wildlife Health Center, 6006 Schroeder Rd, Madison, WI, 53711, USA.
Joel PutnamU.S. Geological Survey, Upper Midwest Environmental Sciences Center, 2630 Fanta Reed Rd, La Crosse, WI, 54603, USA.
Tony L GoldbergDepartment of Pathobiological Sciences and Freshwater and Marine Sciences Program, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI, 53706, USA. tony.goldberg@wisc.edu.
University of Wisconsin–Madison · USUnited States Fish and Wildlife Service · USNational Wildlife Health Center · USUnited States Geological Survey · USUpper Midwest Environmental Sciences Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Freshwater mussels (order Unionida) are among the world's most biodiverse but imperiled taxa. Recent unionid mass mortality events around the world threaten ecosystem services such as water filtration, nutrient cycling, habitat stabilization, and food web enhancement, but causes have remained elusive. To examine potential infectious causes of these declines, we studied mussels in Clinch River, Virginia and Tennessee, USA, where the endemic and once-predominant pheasantshell (Actinonaias pectorosa) has suffered precipitous declines since approximately 2016. Using metagenomics, we identified 17 novel viruses in Clinch River pheasantshells. However, only one virus, a novel densovirus (Parvoviridae; Densovirinae), was epidemiologically linked to morbidity. Clinch densovirus 1 was 11.2 times more likely to be found in cases (moribund mussels) than controls (apparently healthy mussels from the same or matched sites), and cases had 2.7 (log

Indexed as

AnimalsBiodiversityComputational BiologyDensovirusEcosystemEnvironmental MonitoringGenomeGenomicsOpen Reading FramesParvoviridae InfectionsPhylogenyRiversTennesseeUnionidaeViral LoadVirginia

Identifiers

PMID32879395
PMCPMC7468154
OpenAlexW3082229272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.