Evidence map›Paper›PMID 32879385›Full record

ArticleScientific reports2020

Hippocampal alterations in glutamatergic signaling during amyloid progression in AβPP/PS1 mice.

Kevin N Hascup, Caleigh A Findley, Lindsey N Sime, Erin R Hascup

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Improving our understanding of the biology of aging: findings from the Age-It Research Program.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  3. Lifespan of male and female APP/PS1 and APPJournal of Alzheimer's disease : JAD · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Lifespan of male and female APP/PS1 and APPbioRxiv : the preprint server for biology · 2024
    Article
  9. A combination of ΔNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Neuroprotective Potential of Pyranocoumarins fromAntioxidants (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kevin N HascupDepartment of Neurology, Center for Alzheimer's Disease and Related Disorders, Neurosciences Institute, Southern Illinois University School of Medicine, P.O. Box 19628, Springfield, IL, 62794-9628, USA.
Caleigh A FindleyDepartment of Neurology, Center for Alzheimer's Disease and Related Disorders, Neurosciences Institute, Southern Illinois University School of Medicine, P.O. Box 19628, Springfield, IL, 62794-9628, USA.
Lindsey N SimeDepartment of Neurology, Center for Alzheimer's Disease and Related Disorders, Neurosciences Institute, Southern Illinois University School of Medicine, P.O. Box 19628, Springfield, IL, 62794-9628, USA.
Erin R HascupDepartment of Neurology, Center for Alzheimer's Disease and Related Disorders, Neurosciences Institute, Southern Illinois University School of Medicine, P.O. Box 19628, Springfield, IL, 62794-9628, USA. ehascup@siumed.edu.
Neurosciences Institute · USSouthern Illinois University School of Medicine · US

Funding

Sequelae of SARS-CoV-2 Infection in Alzheimer's DiseaseR01AG061937 · NIA · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI HASCUP, ERIN R · 2018 to 2022
$4.0M
Glutamate neurotransmission in Alzheimer's disease progressionR01AG057767 · NIA · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI HASCUP, ERIN R · 2018 to 2022
$3.2M
NIA NIH HHS R01 AG057767NIA NIH HHS R01 AG061937
6 · The paper itself

Abstract

Our previous research demonstrated that soluble amyloid-β (Aβ)

Indexed as

Signal TransductionAlzheimer DiseaseAmyloidAmyloid beta-Protein PrecursorAnimalsCognitionGlutamic AcidGlutamineHippocampusMaleMaze LearningMemoryMiceMice, Inbred C57BLMicroelectrodesAmyloidAmyloid beta-Protein PrecursorAPP protein, mouseGlutamic AcidGlutamine

Identifiers

PMID32879385
PMCPMC7467928
OpenAlexW3082616876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.