Evidence map›Paper›PMID 32878994›Full record

ArticleRMD open2020

National registry for patients with inflammatory rheumatic diseases (IRD) infected with SARS-CoV-2 in Germany (ReCoVery): a valuable mean to gain rapid and reliable knowledge of the clinical course of SARS-CoV-2 infections in patients with IRD.

Rebecca Hasseli, Ulf Mueller-Ladner, Tim Schmeiser, Bimba F Hoyer, Andreas Krause, Hanns-Martin Lorenz, Anne Constanze Regierer, Jutta G Richter, Anja Strangfeld, Reinhard E Voll and 3 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Guideline
  2. [The German COVID-19 rheumatism register].Zeitschrift fur Rheumatologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Rebecca Hasseli *Department of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany r.hasseli@kerckhoff-klinik.de.ORCID 0000-0002-2982-8253
Ulf Mueller-Ladner *Department of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
Tim Schmeiser *Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
Bimba F HoyerDepartment of Rheumatology and Clinical Immunology, Clinic for Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Andreas KrauseDepartment of Rheumatology, Clinical Immunology and Osteology, Immanuel Hospital Berlin, Berlin, Germany.
Hanns-Martin LorenzDepartment of Rheumatology, University of Heidelberg, Heidelberg, Germany.
Anne Constanze RegiererEpidemiology Unit, German Rheumatism Research Centre, Berlin, Germany.ORCID 0000-0003-2456-4049
Jutta G RichterDepartment of Rheumatology and Hiller Research Unit, Heinrich-Heine-University, Medical Faculty, Duesseldorf, Germany.
Anja StrangfeldEpidemiology Unit, German Rheumatism Research Centre, Berlin, Germany.
Reinhard E VollDepartment of Rheumatology and Clinical Immunology, University Medical Center, Faculty of Medicine, Albert-Ludwigs University of Freiburg, Freiburg, Germany.
Alexander PfeilDepartment of Internal Medicine III, University Hospital Jena, Jena, Germany.
Hendrik Schulze-Koops *Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, University of Munich, Munich, Germany.
Christof Specker *Department of Rheumatology and Clinical Immunology, KEM Kliniken Essen-Mitte,Essen, Germany.
German Rheumatism Research Centre · DEJustus-Liebig-Universität Gießen · DEHeidelberg University · DEHeinrich Heine University Düsseldorf · DEImmanuel Krankenhaus · DEJena University Hospital · DEKliniken Essen-Mitte · DELudwig-Maximilians-Universität München · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with inflammatory rheumatic diseases (IRD) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be at risk to develop a severe course of COVID-19. The influence of immunomodulating drugs on the course of COVID-19 is unknown. To gather knowledge about SARS-CoV-2 infections in patients with IRD, we established a registry shortly after the beginning of the pandemic in Germany.

methodsUsing an online questionnaire (www.COVID19-rheuma.de), a nationwide database was launched on 30 March 2020, with appropriate ethical and data protection approval to collect data of patients with IRD infected with SARS-CoV-2. In this registry, key clinical and epidemiological parameters-for example, diagnosis of IRD, antirheumatic therapies, comorbidities and course of the infection-are documented.

resultsUntil 25 April 2020, data from 104 patients with IRD infected with SARS-CoV-2 were reported (40 males; 63 females; 1 diverse). Most of them (45%) were diagnosed with rheumatoid arthritis, 59% had one or more comorbidities and 42% were treated with biological disease-modifying antirheumatic drugs. Hospitalisation was reported in 32% of the patients. Two-thirds of the patients already recovered. Unfortunately, 6 patients had a fatal course.

conclusionsIn a short time, a national registry for SARS-CoV2-infected patients with IRD was established. Within 4 weeks, 104 cases were documented. The registry enables to generate data rapidly in this emerging situation and to gain a better understanding of the course of SARS-CoV2-infection in patients with IRD, with a distinct focus on their immunomodulatory therapies. This knowledge is valuable for timely information of physicians and patients with IRD, and shall also serve for the development of guidance for the management of patients with IRD during this pandemic.

Indexed as

RegistriesAdultAgedAged, 80 and overAntirheumatic AgentsArthritis, PsoriaticArthritis, RheumatoidBetacoronavirusBiological ProductsCoronavirus InfectionsCOVID-19FemaleGermanyGranulomatosis with PolyangiitisHospitalizationHumansAntirheumatic AgentsBiological ProductsAntirheumatic AgentsAutoimmune DiseasesCommunicable DiseasesEpidemiologyHealth services researchImported

Identifiers

PMID32878994
PMCPMC7507994
OpenAlexW3082923229

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.