Evidence map›Paper›PMID 32878986›Full record

ArticleThe Journal of biological chemistry2020

Structural basis for the interaction of Shiga toxin 2a with a C-terminal peptide of ribosomal P stalk proteins.

Michael J Rudolph, Simon A Davis, Nilgun E Tumer, Xiao-Ping Li

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael J RudolphNew York Structural Biology Center, New York, New York, USA.
Simon A DavisNew York Structural Biology Center, New York, New York, USA.
Nilgun E TumerDepartment of Plant Biology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA. Electronic address: tumer@sebs.rutgers.edu.
Xiao-Ping LiDepartment of Plant Biology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA. Electronic address: xpli@sebs.rutgers.edu.
New York Structural Biology Center · USRutgers, The State University of New Jersey · US

Funding

What makes ricin ToxicR01AI072425 · NIAID · RUTGERS, THE STATE UNIV OF N.J. · PI TUMER, NILGUN E · 2007 to 2021
$5.8M
Assay development and screening for inhibitors targeting Shiga toxin 2R01AI141635 · NIAID · RUTGERS, THE STATE UNIV OF N.J. · PI LI, XIAO-PING · 2019 to 2022
$2.1M
A Biacore 8K SystemS10OD026750 · OD · RUTGERS, THE STATE UNIV OF N.J. · PI TUMER, NILGUN E · 2019 to 2019
$385k
NIAID NIH HHS R01 AI072425NIAID NIH HHS R01 AI141635NIH HHS S10 OD026750
6 · The paper itself

Abstract

The principal virulence factor of human pathogenic enterohemorrhagic

Indexed as

Amino Acid SequenceBinding SitesCrystallography, X-RayHumansMolecular Dynamics SimulationPeptidesProtein BindingRibosomal ProteinsRibosomesRicinShiga Toxin 2TrichosanthinPeptidesRibosomal ProteinsRicinShiga Toxin 2Trichosanthinbacterial toxinE. coliEscherichia coliP1/P2 proteinribosomal stalkribosomeribosome inactivating proteinRIPShiga toxintoxintranslation

Identifiers

PMID32878986
PMCPMC7667979
OpenAlexW3082590483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.