Evidence map›Paper›PMID 32878966›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2020

Modeling Tubercular ESX-1 Secretion Using Mycobacterium marinum.

Alexandra E Chirakos, Ariane Balaram, William Conrad, Patricia A Champion

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Tyloxapol inhibits ESX-1 secretion inJournal of bacteriology · 2026
    Article
  4. PDIM/PGL-deficientMicrobiology resource announcements · 2026
    Article
  5. Article
  6. Assembly of theMicrobiology spectrum · 2025
    Article
  7. Pathogens (Basel, Switzerland) · 2025
    Review
  8. Journal of bacteriology · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. N-terminal proteomics ofMicrobiology resource announcements · 2024
    Article
  13. Article
  14. Frontiers in medicine · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexandra E ChirakosDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Ariane BalaramDepartment of Biology, Lake Forest College, Lake Forest, Illinois, USA.
William ConradDepartment of Chemistry, Lake Forest College, Lake Forest, Illinois, USA conrad@mx.lakeforest.edu pchampio@nd.edu.
Patricia A ChampionDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA conrad@mx.lakeforest.edu pchampio@nd.edu.ORCID 0000-0002-6733-596X
Lake Forest College · USUniversity of Notre Dame · US

Funding

Exploration of the genetic interaction between secreted virulence determinants from pathogenic mycobacteriaR21AI142127 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHAMPION, PATRICIA A · 2019 to 2020
$425k
Mechanisms of ESX-1-dependent Gene Expression in Pathogenic MycobacteriaR21AI149235 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHAMPION, PATRICIA A · 2020 to 2021
$425k
NIAID NIH HHS R21 AI142127NIAID NIH HHS R21 AI149235
6 · The paper itself

Abstract

Pathogenic mycobacteria cause chronic and acute diseases ranging from human tuberculosis (TB) to nontubercular infections.

Indexed as

AnimalsBacterial ProteinsGene Expression Regulation, BacterialHost-Pathogen InteractionsHumansModels, BiologicalMycobacterium marinumMycobacterium tuberculosisProtein TransportTuberculosisType VII Secretion SystemsVirulenceBacterial ProteinsType VII Secretion SystemsESX-1mycobacterial pathogenesisMycobacterium marinumprotein secretiontype VII secretion

Identifiers

PMID32878966
PMCPMC8570393
OpenAlexW3082181208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.