Evidence map›Paper›PMID 32878952›Full record

ArticleJournal of clinical microbiology2020

A Phylogeny-Informed Proteomics Approach for Species Identification within the Burkholderia cepacia Complex.

Honghui Wang, Ousmane H Cissé, Thomas Bolig, Steven K Drake, Yong Chen, Jeffrey R Strich, Jung-Ho Youn, Uchenna Okoro, Avi Z Rosenberg, Junfeng Sun and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Specific biomarker mining and rapid detection ofFrontiers in microbiology · 2023
    Article
  5. Methodological tools to study species of the genus Burkholderia.Applied microbiology and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Honghui Wang *Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Ousmane H Cissé *Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-2990-2185
Thomas BoligCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Steven K DrakeCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Yong ChenProteomics Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Jeffrey R StrichCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Jung-Ho YounDepartment of Laboratory Medicine, Clinical Center, Microbiology Service, National Institutes of Health, Bethesda, Maryland, USA.
Uchenna OkoroCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Avi Z RosenbergKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Junfeng SunCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
John J LiPumaDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Anthony F Suffredini *Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA asuffredini@cc.nih.gov john.dekker@nih.gov.
John P Dekker *Department of Laboratory Medicine, Clinical Center, Microbiology Service, National Institutes of Health, Bethesda, Maryland, USA asuffredini@cc.nih.gov john.dekker@nih.gov.ORCID 0000-0002-3701-5228
National Institutes of Health Clinical Center · USNational Institutes of Health · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ancestral genetic exchange between members of many important bacterial pathogen groups has resulted in phylogenetic relationships better described as networks than as bifurcating trees. In certain cases, these reticulated phylogenies have resulted in phenotypic and molecular overlap that challenges the construction of practical approaches for species identification in the clinical microbiology laboratory.

Indexed as

Burkholderia cepaciaBurkholderia cepacia complexBurkholderia InfectionsBurkholderiaChromatography, LiquidHumansPhylogenyProteomicsTandem Mass Spectrometryclinical microbiologycomputational biologygenomicsmass spectrometrynetwork phylogenyproteomics

Identifiers

PMID32878952
PMCPMC7587091
OpenAlexW3082275277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.