Evidence map›Paper›PMID 32878927›Full record

ArticlemSphere2020

Transcriptional Profiling Suggests T Cells Cluster around Neurons Injected with Toxoplasma gondii Proteins.

Emily F Merritt, Hannah J Johnson, Zhee Sheen Wong, Adam S Buntzman, Austin C Conklin, Carla M Cabral, Casey E Romanoski, Jon P Boyle, Anita A Koshy

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. mBio · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Emily F Merritt *Department of Immunology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-9449-4683
Hannah J Johnson *Neuroscience Graduate Interdisciplinary Program, University of Arizona, Tucson, Arizona, USA.
Zhee Sheen WongDepartment of Biological Sciences, Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Adam S BuntzmanBIO5 Institute, University of Arizona, Tucson, Arizona, USA.
Austin C ConklinDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, Arizona, USA.
Carla M CabralDepartment of Immunology, University of Arizona, Tucson, Arizona, USA.
Casey E RomanoskiBIO5 Institute, University of Arizona, Tucson, Arizona, USA.
Jon P BoyleDepartment of Biological Sciences, Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Anita A KoshyDepartment of Immunology, University of Arizona, Tucson, Arizona, USA akoshy@arizona.edu.ORCID 0000-0001-8705-3233
University of Arizona · USUniversity of Pittsburgh · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Neuronal Latency and ToxoplasmaR01AI157247 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHRISTOPHER A HUNTER, Anita Koshy · 2020 to 2026
$4.7M
Comparative and functional genomics of Toxoplasma and Hammondia hammondiR01AI116855 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYLE, JON P · 2015 to 2024
$3.2M
Defining neuron-Toxoplasma gondii interactions that mediate CNS toxoplasmosisR01NS095994 · NINDS · UNIVERSITY OF ARIZONA · PI KOSHY, ANITA · 2016 to 2020
$2.0M
Mechanisms of ERG in Endothelial ActivationR01HL147187 · NHLBI · UNIVERSITY OF ARIZONA · PI ROMANOSKI, CASEY E · 2019 to 2023
$1.9M
Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training ProgramT32AG058503 · NIA · UNIVERSITY OF ARIZONA · PI Kristian Paul Doyle, JANKO Z. NIKOLICH · 2019 to 2026
$1.9M
Translational research in Alzheimer’s Disease and Related Dementias (TRADD)T32AG061897 · NIA · UNIVERSITY OF ARIZONA · PI BRINTON, ROBERTA EILEEN · 2018 to 2022
$1.3M
National Science Foundation DBI-0735191National Science Foundation DBI-1265383National Science Foundation DBI-1743442NHLBI NIH HHS R01 HL147187NHLBI NIH HHS T32 HL007249NIAID NIH HHS R01 AI116855NIAID NIH HHS R01 AI157247NIA NIH HHS T32 AG058503NIA NIH HHS T32 AG061897NIEHS NIH HHS P30 ES006694NINDS NIH HHS R01 NS095994
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCD8-Positive T-LymphocytesGene Expression ProfilingHost-Pathogen InteractionsLaser Capture MicrodissectionMiceMonocytesNeuronsProtozoan ProteinsSequence Analysis, RNAToxoplasmaToxoplasmosisProtozoan Proteinshost-pathogen interactionsimmunologylaser capture microdissectionneuroscienceRNA-seqToxoplasma gondiitranscriptomics

Identifiers

PMID32878927
PMCPMC7471001
OpenAlexW3082095152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.