Evidence map›Paper›PMID 32878902›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Optogenetic Stimulation of Type I GAD65

Caitlin Baumer-Harrison, Martin A Raymond, Thomas A Myers, Kolbe M Sussman, Spencer T Rynberg, Amanda P Ugartechea, Dean Lauterbach, Thomas G Mast, Joseph M Breza

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. METTL3-mediated mInternational journal of oral science · 2022
    Article
  9. Taste Receptor Signaling.Handbook of experimental pharmacology · 2022
    Article
  10. Pharmacology of T2R Mediated Host-Microbe Interactions.Handbook of experimental pharmacology · 2022
    Article
  11. Article
  12. Article
  13. Cellular Diversity and Regeneration in Taste Buds.Current opinion in physiology · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Caitlin Baumer-HarrisonDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Martin A RaymondDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.ORCID 0000-0002-5202-814X
Thomas A MyersDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Kolbe M SussmanDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Spencer T RynbergDepartment of Biology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Amanda P UgartecheaDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Dean LauterbachDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Thomas G MastDepartment of Biology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Joseph M BrezaDepartment of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197 jbreza1@emich.edu.
Eastern Michigan University · US

Funding

Lightly Salted: An Optogenetic Approach to Uncover the Role of Type I Cells in Salt Taste TransductionR21DC016990 · NIDCD · EASTERN MICHIGAN UNIVERSITY · PI BREZA, JOSEPH MICHAEL · 2018 to 2020
$430k
NIDCD NIH HHS R21 DC016990
6 · The paper itself

Abstract

Mammalian taste buds are comprised of specialized neuroepithelial cells that act as sensors for molecules that provide nutrition (e.g., carbohydrates, amino acids, and salts) and those that are potentially harmful (e.g., certain plant compounds and strong acids). Type II and III taste bud cells (TBCs) detect molecules described by humans as "sweet," "bitter," "umami," and "sour." TBCs that detect metallic ions, described by humans as "salty," are undefined. Historically, type I glial-like TBCs have been thought to play a supportive role in the taste bud, but little research has been done to explore their role in taste transduction. Some evidence implies that type I cells may detect sodium (Na

Indexed as

AmilorideAnimalsAppetiteChannelrhodopsinsCranial NervesDiureticsFemaleFood PreferencesGlutamate DecarboxylaseMaleMiceOptogeneticsSensory Receptor CellsSodiumSodium ChlorideTaste BudsAmilorideChannelrhodopsinsDiureticsGlutamate Decarboxylaseglutamate decarboxylase 2SodiumSodium ChlorideGAD65nucleus tractus solitariusoptogeneticspreferencesensory systemstaste

Identifiers

PMID32878902
PMCPMC7548691
OpenAlexW3081821563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.