Evidence map›Paper›PMID 32878836›Full record

ArticleBMJ case reports2020

Hyponatraemia compounding pre-eclamptic toxaemia in a patient with type 1 diabetes.

Emily Briggs, Orene Greer, Nishel Mohan Shah, Natasha Singh

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emily BriggsDepartment of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK emily.briggs7@nhs.net.
Orene GreerDepartment of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK.
Nishel Mohan ShahDepartment of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK.ORCID http://orcid.org/0000-0002-5694-9915
Natasha SinghDepartment of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK.
Chelsea and Westminster Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of profound, symptomatic hyponatraemia in association with pre-eclamptic toxaemia (PET) in a 38-year-old nulliparous woman with type 1 diabetes mellitus. This patient developed hypertension and proteinuria at 31+6 weeks' gestation and was admitted for management of pre-eclampsia. Severe headache, visual disturbance and nausea were associated with a hyponatraemia of 115 mmol/L followed by ketoacidosis. This was reversed through fluid restriction, supplementation with 1.8%-3.0% hypertonic saline and a volume-reduced variable-rate insulin infusion. Clinical stability was achieved and she was subsequently worked up for an induction of labour for worsening pre-eclampsia. Hyponatraemia in the context of PET has been previously reported as rare. However, it has complications that may significantly compound the sequelae of severe PET. We propose that specific and focused monitoring of serum sodium levels should become common practice in the management of women with this condition to allow for timely, measured correction of abnormalities.

Indexed as

AdultDiabetes Mellitus, Type 1FemaleHumansHyponatremiaInsulinPre-EclampsiaPregnancySaline Solution, HypertonicSeverity of Illness IndexToxemiaTreatment OutcomeInsulinSaline Solution, Hypertonicdiabetesendocrinologyobstetrics and gynaecology

Identifiers

PMID32878836
PMCPMC7470496
OpenAlexW3082785323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.