Evidence map›Paper›PMID 32878831›Full record

ArticleBMJ case reports2020

Management of large congenital chylous ascites in a preterm infant: fetal and neonatal interventions.

Loo Sooklin, Amudha Jayanthi Anand, Victor Samuel Rajadurai, Suresh Chandran

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Guideline
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  3. Guideline
  4. Guideline
  5. Article
  6. Review
  7. Octreotide and direct/indirect lung injury.Research in pharmaceutical sciences · 2025
    Review
  8. Article
  9. Fetal Ascites: Its Prenatal Management and Postnatal Outcome.Journal of obstetrics and gynaecology of India · 2024
    Article
  10. Propranolol As a Treatment Option for Chylous Effusions and Chylous Ascites in Fetuses and Neonates: A Systematic Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024
    Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Loo SooklinNeonatology, KK Women's and Children's Hospital, Singapore.
Amudha Jayanthi AnandNeonatology, KK Women's and Children's Hospital, Singapore.
Victor Samuel RajaduraiNeonatology, KK Women's and Children's Hospital, Singapore.
Suresh ChandranNeonatology, KK Women's and Children's Hospital, Singapore profschandran2019@gmail.com.ORCID http://orcid.org/0000-0001-5961-7441
Singapore College of Traditional Chinese Medicine · SGKK Women's and Children's Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital chylous ascites is a rare cause of ascites in newborn infants. Its aetiology varies from localised leaky lymphatic duct to genetic syndromes. Most of these cases have transient ascites resolving over time with conservative management but some may progress needing medical as well as surgical treatment. We describe a case of antenatally detected large fetal ascites necessitating abdominal paracentesis and amnioreduction. Marked respiratory distress at birth required urgent abdominal paracentesis to relieve symptoms. The infant initially showed a good response to medium chain triglyceride (MCT) based formula milk feeds. Feeds were discontinued for 3 weeks due to sepsis with ileus. On recovery, recommencement of feeds resulted in reaccumulation of ascites. As the response to MCT-based formula was inadequate, octreotide therapy was initiated. Ascites showed remarkable resolution over the next 2 weeks and was discharged home. Follow-up at 5 years of age revealed normal growth and neurodevelopment.

Indexed as

FetoscopyParacentesisChild DevelopmentChild, PreschoolChylous AscitesFemaleHumansInfantInfant FormulaInfant, NewbornInfant, PrematureLongitudinal StudiesOctreotideTreatment OutcomeTriglyceridesUltrasonography, PrenatalOctreotideTriglyceridescongenital disordersneonatal intensive carenutritionultrasonography

Identifiers

PMID32878831
PMCPMC7470640
OpenAlexW3083003934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.