ArticleBMC neurology2020
Increased incidence of Susac syndrome: a case series study.
Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06349603 (Integrated Physiotherapy Approach for Susac Syndrome), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Integrated Physiotherapy Approach for Susac Syndrome: A Comprehensive Case Study
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Clinical Characterization and Ancillary Tests in Susac Syndrome: A Systematic Review.Neurology(R) neuroimmunology & neuroinflammation · 2024Pooled it
- Clinical Characterization and Prognostic Risk Factors of Susac Syndrome: A Retrospective Multicenter Study.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Atypical Presentation of Susac Syndrome in 55-Year-Old: From Unremarkable Stroke Workup to Rapid Diagnosis of "Snowball Strokes" and Successful Immunosuppressive Treatment.Case reports in neurological medicine · 2025Article
- Susac syndrome: A rare pediatric case.Radiology case reports · 2024Article
- The neurocognitive and neuropsychiatric manifestations of Susac syndrome: a brief review of the literature and future directions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- Cognitive outcomes in Susac syndrome: A 2-year neuropsychological follow-up study.European journal of neurology · 2024Article
- Case report: Susac syndrome-two ends of the spectrum, single center case reports and review of the literature.Frontiers in neurology · 2024Article
- Susac syndrome: neurological update (clinical features, long-term observational follow-up and management of sixteen patients).Journal of neurology · 2023Article
- Use of disease assessment tools to increase the value of case reports on Susac syndrome: two case reports.Journal of medical case reports · 2023Article
- Article
- Susac Syndrome: Description of a Single-Centre Case Series.Journal of clinical medicine · 2022Article
- Characteristics and management of Susac syndrome in an emergent country: a multi-center case series from Brazil.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Susac Syndrome: A Rare cause of Bilateral Sensorineural hearing loss from North India-A Case Report with Review of literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Diagnosis, differential diagnosis and misdiagnosis of Susac syndrome.European journal of neurology · 2022Article
- Manifestation of Susac syndrome during interferon beta-1a and glatiramer acetate treatment for misdiagnosed multiple sclerosis: a case report.BMC ophthalmology · 2021Article
- Susac syndrome and pregnancy: a review of published cases and considerations for patient management.Therapeutic advances in neurological disorders · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSusac syndrome (SuS) is a rare condition characterized by a clinical triad of sensorineural hearing loss, branch artery occlusion and encephalopathy. This study reports an increased incidence of SuS in Israel. We describe the clinical characteristics of these patients, diagnostic procedures and the use and subsequent outcomes of newly published treatment guidelines.
methodsThis is a single center retrospective study. Patients who were diagnosed with SuS between July 2017 and August 2018 were enrolled in this study.
resultsSeven patients were diagnosed with SuS according to the diagnostic criteria in a time period of 13 months. The annual incidence was recently evaluated in Austria to be 0.024/100000, therefore, our case series represent at least a 5.4- fold increase in the annual incidence of SuS expected in Israel and a 7-fold increase in the annual incidence expected in our medical center. Mean time from the onset of the symptoms to diagnosis was three weeks and follow-up time was twenty four months. Recent exposure to cytomegalovirus was serologically evident in three patients and one patient had high titer of anti-streptolysin antibody. All patients underwent brain MRI, fluorescein angiography and audiometry. All patients were treated according to the newly recommended guidelines. All patients achieved clinical and radiological stability.
conclusionsWe report of an increased incidence of SuS in Israel. Infectious serological findings may imply a post infectious mechanism. The use of the recommended diagnostic procedures reduced the time to diagnosis. Newly published treatment guidelines led to favorable clinical outcomes.
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