Evidence map›Paper›PMID 32878599›Full record

ArticleBMC neurology2020

Posterior reversible encephalopathy syndrome case report in an untreated, normotensive, ovarian cancer patient in the presence of paraneoplastic antibodies.

Elad Barber, Rijini Nugzar, Vitaly Finkelshtein, Alexander Puzhevsky, Tally Levy

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elad BarberDivision of Gynecologic Oncology, Wolfson Medical Center, Holon, Israel. elad.barber@gmail.com.ORCID http://orcid.org/0000-0001-8199-5692
Rijini NugzarSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Vitaly FinkelshteinSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Alexander PuzhevskySackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tally LevyDivision of Gynecologic Oncology, Wolfson Medical Center, Holon, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPosterior reversible encephalopathy syndrome (PRES) is a rare neurological condition with many associated risk factors. The presentation varies and consists of seizures, impaired visual acuity or visual field deficits, disorders of consciousness, headaches, confusion and focal neurological deficits. The diagnosis relies on clinical presentation and MRI findings. Treatment and prognosis are related to the underlying etiology. CASE PRESENTATION: We present a 58-year-old woman with ovarian cancer who developed symptoms and radiologic signs of PRES with no apparent trigger other than a sudden increase in blood pressure for the first time in her life and before any treatment has begun. Antibodies to collapsin response-mediator protein-5 (CRMP-5), a malignancy related paraneoplastic protein, were identified in her CSF.

conclusionsWe present a novel and intriguing association between PRES and antibodies against CRMP-5 which may highlight a new etiology for this condition.

Indexed as

Blood PressureConfusionFemaleHeadacheHumansMagnetic Resonance ImagingMiddle AgedOvarian NeoplasmsPosterior Leukoencephalopathy SyndromeRisk FactorsSeizuresCRMP5Ovarian cancerParaneoplastic antibodiesPosterior reversible encephalopathy syndromePRES

Identifiers

PMID32878599
PMCPMC7466806
OpenAlexW3082542978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.