Observational studyUnited European gastroenterology journal2020
Oral health and salivary function in ulcerative colitis patients.
Observational study in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis - A systematic review.Acta odontologica Scandinavica · 2025Pooled it
- Insights into Gut Dysbiosis: Inflammatory Diseases, Obesity, and Restoration Approaches.International journal of molecular sciences · 2024Review
- Association of Preterm Birth with Inflammatory Bowel Disease and Salivary Gland Disease: Machine Learning Analysis Using National Health Insurance Data.International journal of environmental research and public health · 2022Article
- Oral manifestations serve as potential signs of ulcerative colitis: A review.Frontiers in immunology · 2022Review
- A potential pathogenic association between periodontal disease and Crohn's disease.JCI insight · 2021Article
- Dental and periodontal disease in patients with inflammatory bowel disease.Clinical oral investigations · 2021Article
- The pathogenic oral-gut-liver axis: new understandings and clinical implications.Expert review of clinical immunology · 2021Review
- Salivary Stress/Immunological Markers in Crohn's Disease and Ulcerative Colitis.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough ulcerative colitis primarily involves the colon, extra-intestinal manifestations are common and oral and dental complaints are no exception.
objectiveThis study aims at evaluating oral and dental health problems and salivary function and composition in ulcerative colitis patients and its correlation with disease activity.
methodsXerostomia Inventory score, (unstimulated/stimulated) salivary flow rates, salivary amylase and mucin/ Mucin 5B levels, self-reported oral and dental complaints, the oral health related quality of life, Simple Clinical Colitis Activity Index and inflammatory bowel disease-specific health related quality of life were determined.
resultsThe cohort consisted of 51 ulcerative colitis patients. Hyposalivation was experienced by 16% of patients under resting conditions and 24% under chewing-stimulated conditions. Xerostomia was not correlated with salivary flow rates. Disease activity did not influence salivary amylase and Mucin 5B concentrations. The Xerostomia Inventory score was correlated with the Simple Clinical Colitis Activity Index (
conclusionThe subjective feeling of a dry mouth (xerostomia) is related to disease activity and disease activity-associated quality of life in ulcerative colitis patients, whereas the objective saliva secretion rate is not. Oral and dental health problems are frequently observed in patients with ulcerative colitis, especially during active disease.
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