Evidence map›Paper›PMID 32878328›Full record

ArticleInternational journal of molecular sciences2020

Aryl Hydrocarbon Receptor Signaling Is Functional in Immune Cells of Rainbow Trout (

Jun-Young Song, Ayako Casanova-Nakayama, Anja-Maria Möller, Shin-Ichi Kitamura, Kei Nakayama, Helmut Segner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jun-Young SongCentre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Ayako Casanova-NakayamaCentre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Anja-Maria MöllerCentre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Shin-Ichi KitamuraCenter for Marine Environmental Studies (CMES), Ehime University, Matsuyama, Ehime 790-8577, Japan.ORCID 0000-0001-7357-3369
Kei NakayamaCenter for Marine Environmental Studies (CMES), Ehime University, Matsuyama, Ehime 790-8577, Japan.
Helmut SegnerCentre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-1783-1295
University of Bern · CHEhime University · JP

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_153427; 31003A_130640; 3100OE_16426
6 · The paper itself

Abstract

The arylhydrocarbon receptor (AhR) is an important signaling pathway in the immune system of mammals. In addition to its physiological functions, the receptor mediates the immunotoxic actions of a diverse range of environmental contaminants that bind to and activate the AhR, including planar halogenated aromatic hydrocarbons (PHAHs or dioxin-like compounds) and polynuclear aromatic hydrocarbons (PAHs). AhR-binding xenobiotics are immunotoxic not only to mammals but to teleost fish as well. To date, however, it is unknown if the AhR pathway is active in the immune system of fish and thus may act as molecular initiating event in the immunotoxicity of AhR-binding xenobiotics to fish. The present study aims to examine the presence of functional AhR signaling in immune cells of rainbow trout (

Indexed as

AnimalsCytochrome P-450 CYP1A1Fish ProteinsHead KidneyLymphocytesNeutrophilsOncorhynchus mykissReceptors, Aryl HydrocarbonCytochrome P-450 CYP1A1Fish ProteinsReceptors, Aryl Hydrocarbonaryl hydrocarbon receptorcytochrome P4501Afishhead kidneyimmune cellsimmune signalingimmunotoxicityrainbow trout

Identifiers

PMID32878328
PMCPMC7503690
OpenAlexW3082740679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.