Evidence map›Paper›PMID 32878320›Full record

ArticleCancers2020

Takahiro Yokose, Yasuaki Kabe, Atsushi Matsuda, Minoru Kitago, Sachiko Matsuda, Miwa Hirai, Tomomi Nakagawa, Yohei Masugi, Takako Hishiki, Yuki Nakamura and 22 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 9 institutions in 1 country.

Takahiro YokoseDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0001-6946-280X
Yasuaki KabeDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0003-0952-011X
Atsushi MatsudaDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
Minoru KitagoDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Sachiko MatsudaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Miwa HiraiDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
Tomomi NakagawaDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yohei MasugiDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Takako HishikiDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yuki NakamuraDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Masahiro ShinodaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hiroshi YagiDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yuta AbeDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Go OshimaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Shutaro HoriDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yutaka NakanoDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Kazufumi HondaDepartment of Biomarkers for Early Detection of Cancer, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Ayumi KashiroDepartment of Biomarkers for Early Detection of Cancer, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Chigusa MorizaneDepartment of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Satoshi NaraDepartment of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Shojiro KikuchiInstitute for Advanced Medical Science, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.
Takahiko ShibaharaDepartment of Oral and Maxillo-Facial Surgery, Tokyo Dental College, Tokyo 102-8159, Japan.
Makoto ItonagaHealthcare Business Division, JVCKENWOOD Corporation, Yokosuka 239-8520, Japan.
Masayuki OnoHealthcare Business Division, JVCKENWOOD Corporation, Yokosuka 239-8520, Japan.
Naoko MinegishiTohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8573 Japan.
Seizo KoshibaTohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8573 Japan.
Masayuki YamamotoTohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8573 Japan.
Atsushi KunoBiotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST); Tsukuba 305-8565, Japan.ORCID 0000-0002-6147-6171
Hiroshi HandaDepartment of Chemical Biology, Tokyo Medical University, Tokyo 160-0023, Japan.ORCID 0000-0001-6656-9521
Michiie SakamotoDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Makoto SuematsuDepartment of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Keio University · JPTohoku University · JPJVC Kenwood (Japan) · JPHyogo Medical University · JPNational Institute of Advanced Industrial Science and Technology · JPNippon Medical School · JPTokyo Dental College · JPTokyo Medical University · JPTokyo National Hospital · JP

Funding

Japan Agency for Medical Research and Development 20cm0106403h0005Japan Agency for Medical Research and Development JP17ek0109166Japan Agency for Medical Research and Development JP17gm0710010Japan Society for the Promotion of Science 18K06921Japan Society for the Promotion of Science 19K18132
6 · The paper itself

Abstract

Pancreatic cancer (PC) is among the most lethal malignancies due to an often delayed and difficult initial diagnosis. Therefore, the development of a novel, early stage, diagnostic PC marker in liquid biopsies is of great significance. In this study, we analyzed the differential glycomic profiling of extracellular vesicles (EVs) derived from serum (two cohorts including 117 PC patients and 98 normal controls) using lectin microarray. The glyco-candidates of PC-specific EVs were quantified using a high-sensitive exosome-counting system, ExoCounter. An absolute quantification system for altered glycan-containing EVs elevated in PC serum was established. EVs recognized by

Indexed as

extracellular vesiclesglycomicslectin microarrayliquid biopsyO-glycanpancreatic cancer

Identifiers

PMID32878320
PMCPMC7563872
OpenAlexW3081689041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.