Evidence map›Paper›PMID 32878291›Full record

ReviewInternational journal of molecular sciences2020

Evolution of

Annamaria Sandomenico, Jwala P Sivaccumar, Menotti Ruvo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 120 citations in OpenAlex.

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  18. Papain expression in theApplied and environmental microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Annamaria SandomenicoIstituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone, 16, 80134 Napoli, Italy.
Jwala P SivaccumarIstituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone, 16, 80134 Napoli, Italy.
Menotti RuvoIstituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone, 16, 80134 Napoli, Italy.ORCID 0000-0001-5997-756X
Institute of Biostructure and Bioimaging · IT

Funding

Ministero della Salute, Italia Progetto di ricerca su cellule CAR-T per patologie ematologiche maligne e per tumori solidiRegione Campania Development of novel therapeutic approaches for treatment-resistant neoplastic diseases (SATIN)Regione Campania NANOCAN, NANOfotonica per la lotta al CANcro
6 · The paper itself

Abstract

Antibodies and antibody-derived molecules are continuously developed as both therapeutic agents and key reagents for advanced diagnostic investigations. Their application in these fields has indeed greatly expanded the demand of these molecules and the need for their production in high yield and purity. While full-length antibodies require mammalian expression systems due to the occurrence of functionally and structurally important glycosylations, most antibody fragments and antibody-like molecules are non-glycosylated and can be more conveniently prepared in

Indexed as

AnimalsBioengineeringEscherichia coliHumansImmunoglobulin FragmentsRecombinant ProteinsSingle-Chain AntibodiesImmunoglobulin FragmentsRecombinant ProteinsSingle-Chain Antibodiesantibody fragmentE. coliFabscFv

Identifiers

PMID32878291
PMCPMC7504322
OpenAlexW3082160870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.