Evidence map›Paper›PMID 32878275›Full record

ArticleInternational journal of molecular sciences2020

Decellularized Extracellular Matrices and Cardiac Differentiation: Study on Human Amniotic Fluid-Stem Cells.

Giulia Gaggi, Andrea Di Credico, Pascal Izzicupo, Silvia Sancilio, Michele Di Mauro, Giovanni Iannetti, Susanna Dolci, Giovanni Amabile, Angela Di Baldassarre, Barbara Ghinassi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

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  16. Advanced Multi-Dimensional Cellular Models as Emerging Reality to ReproduceInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Giulia GaggiHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Andrea Di CredicoHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Pascal IzzicupoHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Silvia SancilioHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Michele Di MauroCardio-Thoracic Surgery Unit, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Cardiovascular Research Institute Maastricht (CARIM), 6202 Maastricht, The Netherlands.
Giovanni IannettiUniversity of Rome La Sapienza, 00185 Rome, Italy.
Susanna DolciDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giovanni AmabileEnthera Srl, 20123 Milan, Italy.
Angela Di BaldassarreHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Barbara GhinassiHaman Anatomy and Cell Differentiation Lab, Department of Medicine and Aging Sciences, University "G.d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
University of Chieti-Pescara · ITMaastricht University Medical Centre · NLSapienza University of Rome · ITUniversity of Rome Tor Vergata · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017ATZ2YKMinistero dell'Istruzione, dell'Università e della Ricerca SIR2014-RBSI140GLQ.
6 · The paper itself

Abstract

Cell therapy with a variety of stem populations is increasingly being investigated as a promising regenerative strategy for cardiovascular (CV) diseases. Their combination with adequate scaffolds represents an improved therapeutic approach. Recently, several biomaterials were investigated as scaffolds for CV tissue repair, with decellularized extracellular matrices (dECMs) arousing increasing interest for cardiac tissue engineering applications. The aim of this study was to analyze whether dECMs support the cardiac differentiation of

Indexed as

Cell DifferentiationTissue EngineeringAmniotic FluidAnimalsCell AdhesionCell ProliferationCollagenDrug CombinationsExtracellular MatrixFemaleHorsesHumansLamininMaleMyocytes, CardiacProteoglycansCollagenDrug CombinationsLamininmatrigelProteoglycansamniotic fluid stem cellsbiomaterialscardiac differentiationcardiac tissue engineeringCardiopoieticAF cellsdecellularized extracellular matrixinduced pluripotent stem cellsL-type calcium channelssarcomeric proteinsscaffolds

Identifiers

PMID32878275
PMCPMC7504221
OpenAlexW3082411958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.