Evidence map›Paper›PMID 32878269›Full record

ArticleTropical medicine and infectious disease2020

Neuroinvasive West Nile Infection with an Unusual Clinical Presentation: A Single-Center Case Series.

Nadia Castaldo, Elena Graziano, Maddalena Peghin, Tolinda Gallo, Pierlanfranco D'Agaro, Assunta Sartor, Tiziana Bove, Roberto Cocconi, Giovanni Merlino, Matteo Bassetti

Abstract readCase Reports
In one paragraph

Article in Tropical medicine and infectious disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Global Perspectives on Arbovirus Outbreaks: A 2020 Snapshot.Tropical medicine and infectious disease · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nadia CastaldoInfectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.
Elena GrazianoInfectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.
Maddalena PeghinInfectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.
Tolinda GalloDepartment of Prevention, Local Health Unit 4 Medio Friuli, 33100 Udine, Italy.
Pierlanfranco D'AgaroDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34100 Trieste, Italy.
Assunta SartorInfectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.
Tiziana BoveAnesthesiology and Intensive Care Medicine, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.ORCID 0000-0002-5489-2898
Roberto CocconiSOC Direzione Medica di Presidio, Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.
Giovanni MerlinoClinical Neurology, University of Udine Medical School, 33100 Udine, Italy.ORCID 0000-0002-6525-9529
Matteo BassettiInfectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2018 West Nile Virus (WNV) season in Europe was characterized by an extremely high infection rate and an exceptionally higher burden when compared to previous seasons. Overall, there was a 10.9-fold increase in incidence in Italy, with 577 human cases, 230 WNV neuroinvasive diseases (WNNV) and 42 WNV-attributed deaths. Methods: in this paper we retrospectively reported the neurological presentation of 7 patients admitted to University Hospital of Udine with a diagnosis of WNNV, especially focusing on two patients who presented with atypical severe brain stem involvement. Conclusions: the atypical features of some of these forms highlight the necessity to stay vigilant and suspect the diagnosis when confronted with neurological symptoms. We strongly encourage clinicians to consider WNNV in patients presenting with unexplained neurological symptoms in mild climate-areas at risk.

Indexed as

artropodesFlavivirusmosquitosneuroinvasivenessvectorWest Nile Virus

Identifiers

PMID32878269
PMCPMC7558676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.