Evidence map›Paper›PMID 32878230›Full record

ReviewNutrients2020

Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review.

Atanasio Pandiella-Alonso, Elena Díaz-Rodríguez, Eduardo Sanz

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Adherence with oral nutritional supplements and influencing factors in postoperative patients with digestive tract tumors: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Atanasio Pandiella-AlonsoInstituto de Biología Molecular y Celular del Cáncer, CSIC-IBSAL and CIBERONC, 37007 Salamanca, Spain.
Elena Díaz-RodríguezInstituto de Biología Molecular y Celular del Cáncer, CSIC-IBSAL and CIBERONC, 37007 Salamanca, Spain.
Eduardo SanzCatalysis S.L., 28016 Madrid, Spain.
Centro de Investigación del Cáncer · ESInstituto de Catálisis y Petroleoquímica · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different preclinical models as well as clinical trials is reviewed, paying special attention to the mechanism of action and quality of life improvement properties of this nutritional supplement. Molecularly, its mode of action includes a double edge role on tumor biology, that involves a slowdown in cell proliferation accompanied by cell death induction. Given the safety and good tolerability of OOS, and its potentiation of the antitumoral effect of other standard of care drugs, OOS may be used in the oncology clinic in combination with conventional therapies.

Indexed as

Dietary SupplementsAmino AcidsAnimalsAntineoplastic AgentsApoptosisAscorbic AcidCell Line, TumorCell ProliferationCinnamomum zeylanicumDisease Models, AnimalDrug Evaluation, PreclinicalFolic AcidGlucosamineGlycyrrhizaHumansNeoplasmsAmino AcidsAntineoplastic AgentsAscorbic AcidFolic AcidGlucosamineOcoxinPantothenic AcidPlant ExtractsSucroseTeatrichlorosucroseVitamin B 12Vitamin B 6Zinc Sulfateantioxidantantitumoralnatural productnutritional supplementocoxin

Identifiers

PMID32878230
PMCPMC7551453
OpenAlexW3082344775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.