Evidence map›Paper›PMID 32878226›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Elucidation of the Molecular Mechanism of Wet Granulation for Pharmaceutical Standard Formulations in a High-Speed Shear Mixer Using Near-Infrared Spectroscopy.

Ryo Omata, Yusuke Hattori, Tetsuo Sasaki, Tomoaki Sakamoto, Makoto Otsuka

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ryo OmataFaculty of Pharmacy, Musashino University, 1-1-20 Shinmachi, Nishi-Tokyo, Tokyo 202-8585, Japan.
Yusuke HattoriFaculty of Pharmacy, Musashino University, 1-1-20 Shinmachi, Nishi-Tokyo, Tokyo 202-8585, Japan.
Tetsuo SasakiGraduate School of Medical Photonics, Shizuoka University, 3-5-1 Jyohoku, Naka-ku, Hamamatsu 432-8561, Shizuoka, Japan.ORCID 0000-0002-3922-3098
Tomoaki SakamotoDivision of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki City 210-9501, Kanagawa, Japan.
Makoto OtsukaFaculty of Pharmacy, Musashino University, 1-1-20 Shinmachi, Nishi-Tokyo, Tokyo 202-8585, Japan.
Musashino University · JPNational Institute of Health Sciences · JPShizuoka University · JP

Funding

Japan Agency for Medical Research and Development JP19mk0101105h0102Japan Society for the Promotion of Sciences KAKENHI (B) 16H03882Musashino University Creating Happiness Incubation 2019-23
6 · The paper itself

Abstract

The granulation process of pharmaceutical standard formulation in a high-speed shear wet granulation (HSWG) was measured by in-line near-infrared spectroscopy (NIRS) and agitation power consumption (APC) methods. The F-1, F-2, and F-3 formulations (500 g) contained 96%

Indexed as

agitation power consumptionhigh-speed shear wet granulationmonitoring by in-line near-infrared spectroscopypartial least-squares regressionparticle aggregationregression vectors

Identifiers

PMID32878226
PMCPMC7559106
OpenAlexW3082972806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.