Evidence map›Paper›PMID 32878206›Full record

ArticleCancers2020

Expression Profiling of Extracellular Matrix Genes Reveals Global and Entity-Specific Characteristics in Adenoid Cystic, Mucoepidermoid and Salivary Duct Carcinomas.

Christoph Arolt, Moritz Meyer, Franziska Hoffmann, Svenja Wagener-Ryczek, David Schwarz, Lisa Nachtsheim, Dirk Beutner, Margarete Odenthal, Orlando Guntinas-Lichius, Reinhard Buettner and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. The Multifaced Role of Collagen in Cancer Development and Progression.International journal of molecular sciences · 2024
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  13. Collagen XI alpha 1 chain, a potential therapeutic target for cancer.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Christoph AroltInstitute of Pathology, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Moritz MeyerDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Franziska HoffmannDepartment of Otorhinolaryngology, MALDI Imaging and Innovative Biophotonics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-6872-924X
Svenja Wagener-RyczekInstitute of Pathology, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
David SchwarzDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Lisa NachtsheimDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Dirk BeutnerDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany.
Margarete OdenthalInstitute of Pathology, Medical Faculty, University of Cologne, 50937 Cologne, Germany.ORCID 0000-0002-2424-0960
Orlando Guntinas-LichiusDepartment of Otorhinolaryngology, Head and Neck Surgery, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-9671-0784
Reinhard BuettnerInstitute of Pathology, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Ferdinand von EggelingDepartment of Otorhinolaryngology, MALDI Imaging, Core Unit Proteome Analysis, DFG Core Unit Jena Biophotonic and Imaging Laboratory (JBIL), Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-8062-6999
Jens Peter KlußmannDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
Alexander QuaasInstitute of Pathology, Medical Faculty, University of Cologne, 50937 Cologne, Germany.
University of Cologne · DEJena University Hospital · DEUniversitätsmedizin Göttingen · DE

Funding

Marga und Walter Boll-Stiftung DB210-04.00-15
6 · The paper itself

Abstract

The composition of the extracellular matrix (ECM) plays a pivotal role in tumour initiation, metastasis and therapy resistance. Until now, the ECM composition of salivary gland carcinomas (SGC) has not been studied. We quantitatively analysed the mRNA of 28 ECM-related genes of 34 adenoid cystic (AdCy;

Indexed as

COL11A1COL27A1extracellular matrix (ECM)salivary gland carcinoma

Identifiers

PMID32878206
PMCPMC7564650
OpenAlexW3081648059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.