Evidence map›Paper›PMID 32878146›Full record

ReviewJournal of clinical medicine2020

Photo and Plasma Activation of Dental Implant Titanium Surfaces. A Systematic Review with Meta-Analysis of Pre-Clinical Studies.

Paolo Pesce, Maria Menini, Gregorio Santori, Emanuele De Giovanni, Francesco Bagnasco, Luigi Canullo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolo PesceDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0001-8726-4145
Maria MeniniDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0001-6503-1201
Gregorio SantoriDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.
Emanuele De GiovanniDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.
Francesco BagnascoDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.
Luigi CanulloPrivate Practice, Via Nizza, 46, 00198 Rome, Italy.ORCID 0000-0001-9875-2929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUltraviolet (UV) and non-thermal plasma functionalization are surface treatment modalities that seem able to improve osseointegration. The aim of this systematic review and meta-analysis is to assess the effect of the two methods and possible differences. MATERIALS AND

methodsThe systematic research of pre-clinical animal studies was conducted up to May 2020 in the databases PubMed/Medline, Scopus and the Cochrane Lybrary. A meta-analysis was performed by using the DerSimonian-Laird estimator in random-effects models.

resultsThrough the digital search, 518 articles were identified; after duplicate removal and screening process 10 papers were included. Four studies evaluating UV treatment in rabbits were included in the meta-analysis. The qualitative evaluation of the included studies showed that both UV photofunctionalization and non-thermal plasma argon functionalization of titanium implant surfaces might be effective in vivo to improve the osseointegration. The meta-analysis on four studies evaluating UV treatment in rabbits showed that bone to implant contact values (expressed as standardized mean differences and raw mean differences) were significantly increased in the bio-activated groups when follow-up times were relatively homogeneous, although a high heterogeneity (

conclusionsThe present systematic review and meta-analysis on pre-clinical studies demonstrated that chair-side treatment of implants with UV or non-thermal plasma appear to be effective for improving osseointegration. This systematic review supports further clinical trials on this topic.

Indexed as

dental implantsnon-thermal plasma functionalizationosseointegrationUV photofunctionalization

Identifiers

PMID32878146
PMCPMC7565759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.