Evidence map›Paper›PMID 32877961›Full record

ReviewSeminars in thrombosis and hemostasis2020

Hematology Laboratory Abnormalities in Patients with Coronavirus Disease 2019 (COVID-19).

Bianca Christensen, Emmanuel J Favaloro, Giuseppe Lippi, Elizabeth M Van Cott

Open access · bronzeAbstract readReview
In one paragraph

Review in Seminars in thrombosis and hemostasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. To Clot or Not to Clot: Is That the Question?Journal of clinical medicine · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Autoimmune Diseases Affecting Hemostasis: A Narrative Review.International journal of molecular sciences · 2022
    Review
  16. Coagulation Profile of COVID-19 Patients.Life (Basel, Switzerland) · 2022
    Review
  17. Recent Chronology of COVID-19 Pandemic.Frontiers in public health · 2022
    Review
  18. COVID-19-related laboratory coagulation findings.International journal of laboratory hematology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Bianca ChristensenDepartment of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
Emmanuel J FavaloroLaboratory Haematology, Institute of Clinical Pathology and Medical Research (ICPMR), NSW Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia.
Giuseppe LippiSection of Clinical Biochemistry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy.
Elizabeth M Van CottDepartment of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
Massachusetts General Hospital · USCharles Sturt University · AUUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past few months, Coronavirus Disease 2019 (COVID-19) has spread across much of the world leading to a pandemic. Many infected individuals do not experience signs or symptoms, or experience only mild symptoms, whilst a subset experience severe disease, which is often fatal. A number of laboratory tests have been found to be abnormal in hospitalized patients, and some studies suggest some of these tests can predict an unfavorable outcome. These include markers of acute phase reaction (elevated C-reactive protein, erythrocyte sedimentation rate, white blood cell count, fibrinogen, procalcitonin, factor VIII, von Willebrand factor), signs of tissue injury (elevated lactic dehydrogenase, alanine aminotransferase, cardiac troponins), changes in hemostasis and coagulation (elevated D-dimer, prolonged prothrombin time, decreased platelets, decreased antithrombin, elevated factor VIII and von Willebrand factor), and decreased lymphocytes. Additional studies are needed to confirm the most ideal panel of tests, and to confirm the efficiency of laboratory tests to predict clinical outcome, as well as the ideal anticoagulation management.

Indexed as

AnticoagulantsBetacoronavirusBlood Coagulation DisordersClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingCritical CareHematologyHumansIntensive Care UnitsPandemicsPneumonia, ViralPrognosisRiskSARS-CoV-2Anticoagulants

Identifiers

PMID32877961
PMCPMC7645834
OpenAlexW3082821075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.