Evidence map›Paper›PMID 32877838›Full record

ArticleJournal of communication disorders

Factor analysis of signs of childhood apraxia of speech.

Karen V Chenausky, Amanda Brignell, Angela Morgan, Danielle Gagné, Andrea Norton, Helen Tager-Flusberg, Gottfried Schlaug, Aaron Shield, Jordan R Green

Open access · greenAbstract read
In one paragraph

Article in Journal of communication disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. The value of genomic testing in severe childhood speech disorders.European journal of human genetics : EJHG · 2024
    Article
  8. Article
  9. Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  10. Comorbidity and Severity in Childhood Apraxia of Speech: A Retrospective Chart Review.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
  11. Review
  12. Article
  13. Process-Oriented Profiling of Speech Sound Disorders.Children (Basel, Switzerland) · 2022
    Article
  14. Malocclusion in children with speech sound disorders and motor speech involvement: a cross-sectional clinical study in Swedish children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Karen V ChenauskySpeech and Feeding Disorders Lab, Massachusetts General Hospital Institute of Health Professions, Boston, USA; Department of Neurology, Harvard Medical School, Boston, USA; Center for Autism Research Excellence, Department of Pyschological and Brain Sciences, Boston University, Boston, USA. Electronic address: kvchenausky@mghihp.edu.
Amanda BrignellSpeech and Language, Murdoch Children's Research Institute, Melbourne, Australia; Department of Audiology and Speech Pathology, University of Melbourne, Melbourne, Australia. Electronic address: amanda.brignell@mcri.edu.au.
Angela MorganSpeech and Language, Murdoch Children's Research Institute, Melbourne, Australia; Department of Audiology and Speech Pathology, University of Melbourne, Melbourne, Australia. Electronic address: angela.morgan@mcri.edu.au.
Danielle GagnéSpeech and Feeding Disorders Lab, Massachusetts General Hospital Institute of Health Professions, Boston, USA. Electronic address: dcgagne@mghihp.edu.
Andrea NortonBrain Repair and Neurorestoration Center, Baystate Medical Center, Springfield Massachusetts, USA. Electronic address: acnorton@bidmc.harvard.edu.
Helen Tager-FlusbergCenter for Autism Research Excellence, Department of Pyschological and Brain Sciences, Boston University, Boston, USA. Electronic address: htagerf@bu.edu.
Gottfried SchlaugDepartment of Neurology, Harvard Medical School, Boston, USA; Brain Repair and Neurorestoration Center, Baystate Medical Center, Springfield Massachusetts, USA. Electronic address: gschlaug@bidmc.harvard.edu.
Aaron ShieldDepartment of Speech Pathology & Audiology, Miami University, Oxford, Ohio, USA. Electronic address: shielda@miamioh.edu.
Jordan R GreenSpeech and Feeding Disorders Lab, Massachusetts General Hospital Institute of Health Professions, Boston, USA. Electronic address: jgreen2@mghihp.edu.
Baystate Medical Center · USUniversity of Melbourne · AUBoston University · USCenter for Autism and Related Disorders · USHarvard University · USMGH Institute of Health Professions · USMiami University · US

Funding

Predicting and Otimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum DisorderP50DC018006 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI GREEN, JORDAN R · 2019 to 2023
$12.3M
Testing the efficacy of a novel intervention for minimally verbal children with P50DC013027 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI JOSEPH, ROBERT M · 2012 to 2016
$9.4M
Advanced Research Training in Communication Sciences and DisordersT32DC013017 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Cara E. Stepp · 2016 to 2026
$4.9M
Behavioral and Neural Correlates of Melodic Intonation TherapyR01DC008796 · NIDCD · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SCHLAUG, GOTTFRIED · 2008 to 2012
$2.0M
Prolonging Functional Speech in Persons with Amyotrophic Lateral Sclerosis: A Real-Time Virtual Vocal TractK24DC016312 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI GREEN, JORDAN R · 2017 to 2021
$949k
Identifying and Treating Childhood Apraxia of Speech in Minimally Verbal Children with AutismK99DC017490 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI CHENAUSKY, KAREN V · 2019 to 2021
$298k
NIDCD NIH HHS K24 DC016312NIDCD NIH HHS K99 DC017490NIDCD NIH HHS P50 DC013027NIDCD NIH HHS P50 DC018006NIDCD NIH HHS R01 DC008796NIDCD NIH HHS T32 DC013017
6 · The paper itself

Abstract

purposeTo investigate the latent factors underlying signs of childhood apraxia of speech (CAS) in a group of 57 children with CAS.

methodThe speech of 57 children with CAS (aged 3;5-17;0) was coded for signs of CAS. All participants showed at least five signs of CAS and were judged to have CAS by speech pathologists experienced in pediatric speech disorders. Participants were selected to represent a range of severity of CAS: 30 children were verbal and 27 were minimally verbal with comorbid autism. Participants' scores for each sign (the number of times that sign appeared during a child's speech sample) were converted to z-scores, then entered as variables into an exploratory factor analysis. Models were compared using the Akaike Information Criterion (AIC).

resultsThe three-factor model had the lowest AIC and best fit the data. After oblique rotation, syllable segmentation, slow rate, and stress errors loaded most highly on Factor 1. Groping, addition of phonemes other than schwa, and difficulty with coarticulation loaded most highly on Factor 2. Variable errors loaded most highly on Factor 3. Thus, factors were interpreted as being associated with (1) prosody, (2) coarticulation, and (3) inconsistency.

conclusionsResults are consistent with the three consensus criteria for CAS from the American Speech-Language-Hearing Association: Inappropriate prosody, disrupted coarticulatory transitions, and inconsistent errors on repeated tokens. High loading of the syllable segmentation sign on the inappropriate prosody factor also supports the use of a pause-related biomarker for CAS.

Indexed as

ApraxiasSpeech DisordersSpeech-Language PathologyAdolescentChildChild, PreschoolFactor Analysis, StatisticalHumansSpeechAutism spectrum disorderChildhood apraxia of speechMinimally verbal

Identifiers

PMID32877838
PMCPMC7494519
OpenAlexW3061814180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.