ArticleThe Journal of infectious diseases2020
Not Just Endocarditis: Hospitalizations for Selected Invasive Infections Among Persons With Opioid and Stimulant Use Diagnoses-North Carolina, 2010-2018.
Article in The Journal of infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Review
- Patient-Directed Discharge Among Hospitalized Persons With Opioid Use Disorder in the Fentanyl Era: A Scoping Review.American journal of medicine open · 2026Review
- Burden of Injection Drug Use-Related Infection Hospitalizations in Tennessee, 2016-2023.Open forum infectious diseases · 2026Article
- Infectious disease complications associated with opioid use disorder at a southern county hospital: a retrospective chart review.BMC infectious diseases · 2026Article
- "It Eats My Heart": Identifying Knowledge Gaps in Injection Drug-Related Endocarditis Among Hospitalized Patients.Substance use & addiction journal · 2026Article
- Clinical Impact of an Expanded MOUD Access Initiative for Patients Hospitalized With Infections From Intravenous Opioid Use.American journal of medicine open · 2025Article
- Long-term Risk of Serious Infections and Mortality Among Patients Surviving Drug Use-Associated Infective Endocarditis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Question-answering system extracts information on injection drug use from clinical notes.Communications medicine · 2024Article
- Endocarditis, drug use and biological sex: A statewide analysis comparing sex differences in drug use-associated infective endocarditis with other drug-related harms.The International journal on drug policy · 2024Article
- Epidemiology of acute infections in people who inject drugs in Australia.Drug and alcohol review · 2024Review
- Mortality associated with bacterial and fungal infections and overdose among people with drug use diagnoses.Annals of epidemiology · 2023Article
- Article
- Outcomes of Partial Oral Antibiotic Treatment for Complicated Staphylococcus aureus Bacteremia in People Who Inject Drugs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- "They Just Assume That We're All Going to Do the Wrong Thing With It. It's Just Not True": Stakeholder Perspectives About Peripherally Inserted Central Catheters in People Who Inject Drugs.Open forum infectious diseases · 2022Article
- Natural Language Processing and Machine Learning to Identify People Who Inject Drugs in Electronic Health Records.Open forum infectious diseases · 2022Article
- The practice and embodiment of "goofballs": A qualitative study exploring the co-injection of methamphetamines and opioids.The International journal on drug policy · 2022Article
- Comparative 1-Year Outcomes of Invasive Staphylococcus aureus Infections Among Persons With and Without Drug Use: An Observational Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Observational
- Treatment experiences for skin and soft tissue infections among participants of syringe service programs in North Carolina.Harm reduction journal · 2021Article
- Trends in Hospitalizations for Serious Infections Among People With Opioid Use Disorder in Ontario, Canada.Journal of addiction medicineArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWhile increases in overdoses, viral hepatitis, and endocarditis associated with drug use have been well-documented in North Carolina, the full scope of invasive drug-related infections (IDRIs) has not. We characterized trends in IDRIs among hospitalized patients in North Carolina.
methodsWe compared invasive infections that were related or not related to drug use among hospitalized patients aged 18-55 years based on retrospective review of administrative records from 2010-2018. Hospitalizations for endocarditis, central nervous system/spine infections, osteomyelitis, and septic arthritis were labeled as IDRIs if discharge codes included opioid and/or amphetamine misuse. Trends, rates, and distributions were calculated.
resultsAmong 44 851 hospitalizations for the specified infections, 2830 (6.3%) were IDRIs. The proportion of infections attributable to drug use increased from 1.5% (2010) to 13.1% (2018), and the rate grew from 1.2 to 15.1 per 100 000. Compared with those who had non-drug-related infections, patients with IDRIs were younger (median age, 35 vs 46 years), more likely to be non-Hispanic white (81% vs 56%), and had longer hospitalizations (median, 8 vs 6 days). 43% of hospitalizations for IDRIs involved infective endocarditis.
conclusionsThe rate of IDRIs in North Carolina increased substantially during 2010-2018, indicating an urgent need for enhanced infection prevention, harm reduction, and addiction services aimed at community and inpatient settings.
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