ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020
Parasympathetic activity is the key regulator of heart rate variability between decelerations during brief repeated umbilical cord occlusions in fetal sheep.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Fetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study.BJOG : an international journal of obstetrics and gynaecology · 2026Observational
- Circadian patterns of heart rate variability in fetal sheep after hypoxia-ischaemia: A biomarker of evolving brain injury.The Journal of physiology · 2024Article
- Electrocardiography Assessment of Sympatico-Vagal Balance during Resting and Pain Using the Texas Instruments ADS1299.Bioengineering (Basel, Switzerland) · 2023Article
- Increased variability of fetal heart rate during labour: a review of preclinical and clinical studies.BJOG : an international journal of obstetrics and gynaecology · 2022Review
- Heart rate markers for prediction of fetal acidosis in an experimental study on fetal sheep.Scientific reports · 2022Article
- Fetal respiratory movements improve reliability of heart rate variability and suggest a coupling between fetal respiratory arrhythmia and vagal activity.Physiological reports · 2022Article
- Approaches to Preventing Intrapartum Fetal Injury.Frontiers in pediatrics · 2022Review
- Article
- Uterine activity modifies the response of the fetal autonomic nervous system at preterm active labor.Frontiers in endocrinology · 2022Article
- Reply to Smolich and Mynard.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Measurement of fetal parasympathetic activity during labor: a new pathway for evaluation of fetal well-being?American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Reply to the "Letter to the Editor: measurement of fetal parasympathetic activity during labor: a new pathway for evaluation of fetal well-being?"American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fetal heart rate variability (FHRV) is a widely used index of intrapartum well being. Both arms of the autonomic system regulate FHRV under normoxic conditions in the antenatal period. However, autonomic control of FHRV during labor when the fetus is exposed to repeated, brief hypoxemia during uterine contractions is poorly understood. We have previously shown that the sympathetic nervous system (SNS) does not regulate FHRV during labor-like hypoxia. We therefore investigated the hypothesis that the parasympathetic system is the main mediator of intrapartum FHRV. Twenty-six chronically instrumented fetal sheep at 0.85 of gestation received either bilateral cervical vagotomy (
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