Evidence map›Paper›PMID 32876664›Full record

ReviewFEMS microbiology reviews2021

Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations.

Samira Soltani, Riadh Hammami, Paul D Cotter, Sylvie Rebuffat, Laila Ben Said, Hélène Gaudreau, François Bédard, Eric Biron, Djamel Drider, Ismail Fliss

Abstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 237 papers.

0numbers the graph read from it
0cells of the map it votes in
237citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

237 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
  6. Pacin, a novel bacteriocin fromMicrobiology spectrum · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review

177 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samira SoltaniFood Science Department, Faculty of Agriculture and Food Sciences, Université Laval, G1V 0A6 Québec, Canada.
Riadh HammamiSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, 75 Laurier Ave. E, Ottawa, ON K1N 6N5, Canada.
Paul D CotterTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, P61 C996 Ireland.
Sylvie RebuffatMuséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Laboratory Molecules of Communication and Adaptation of Microorganisms (MCAM), UMR 7245 CNRS-MNHN, CP 54, 57 rue Cuvier, 75005 Paris, France.
Laila Ben SaidFood Science Department, Faculty of Agriculture and Food Sciences, Université Laval, G1V 0A6 Québec, Canada.
Hélène GaudreauFood Science Department, Faculty of Agriculture and Food Sciences, Université Laval, G1V 0A6 Québec, Canada.
François BédardFaculty of Pharmacy and Centre de Recherche en Endocrinologie Moléculaire et Oncologique et Génomique Humaine, Université Laval, 2705 Boulevard Laurier, Quebec G1V 4G2, Canada.
Eric BironFaculty of Pharmacy and Centre de Recherche en Endocrinologie Moléculaire et Oncologique et Génomique Humaine, Université Laval, 2705 Boulevard Laurier, Quebec G1V 4G2, Canada.
Djamel DriderInstitut Charles Viollette, Université de Lille, EA 7394, 53955 Villeneuve d'Ascq, France.
Ismail FlissFood Science Department, Faculty of Agriculture and Food Sciences, Université Laval, G1V 0A6 Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, bacteriocins have received substantial attention as antimicrobial compounds. Although bacteriocins have been predominantly exploited as food preservatives, they are now receiving increased attention as potential clinical antimicrobials and as possible immune-modulating agents. Infections caused by antibiotic-resistant bacteria have been declared as a global threat to public health. Bacteriocins represent a potential solution to this worldwide threat due to their broad- or narrow-spectrum activity against antibiotic-resistant bacteria. Notably, despite their role in food safety as natural alternatives to chemical preservatives, nisin remains the only bacteriocin legally approved by regulatory agencies as a food preservative. Moreover, insufficient data on the safety and toxicity of bacteriocins represent a barrier against the more widespread use of bacteriocins by the food and medical industry. Here, we focus on the most recent trends relating to the application of bacteriocins, their toxicity and impacts.

Indexed as

Anti-Infective AgentsBacteriocinsDrug and Narcotic ControlDrug DevelopmentAnti-Infective AgentsBacteriocinsantimicrobialsbacteriocinsgastrointestinal bioavailabilityregulationssafety evaluationtoxicity

Identifiers

PMID32876664
PMCPMC7794045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.