Evidence map›Paper›PMID 32876301›Full record

ArticleRevista de saude publica2020

Recent HIV Infection among men who have sex with men and transgender women in Tijuana.

Britt Skaathun, Heather A Pines, Thomas L Patterson, Shirley J Semple, Jonathan Pekar, Alicia Harvey-Vera, Gudelia Rangel, Sanjay R Mehta

Open access · goldAbstract read
In one paragraph

Article in Revista de saude publica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Britt SkaathunDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
Heather A PinesDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
Thomas L PattersonDepartment of Psychiatry, University of California, San Diego, La Jolla, USA.
Shirley J SempleDepartment of Psychiatry, University of California, San Diego, La Jolla, USA.
Jonathan PekarBioinformatics and Systems Biology Program, University of California, San Diego, La Jolla, USA.
Alicia Harvey-VeraUniversidad Xochicalco, Tijuana, Baja California, Mexico.
Gudelia RangelUnited States-Mexico Border Health Commission, Tijuana, Baja California, Mexico.
Sanjay R MehtaDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, USA.
University of California San Diego · USXochicalco University · MX

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SONIA JAIN · 1994 to 2026
$78.4M
HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
Automation and Evaluation of Real-Time Transmission Network-Based HIV Prevention Services in New York CityR01AI135992 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERTHEIM, JOEL OKRENT · 2018 to 2022
$3.6M
HIV case finding and genetic transmission networks among MSM in Tijuana, MexicoR01DA037811 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, THOMAS L. · 2014 to 2018
$3.2M
Leveraging Networks, Epidemiology, and Epidemic Modeling: Creative Approaches for HIV EliminationK01DA049665 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SKAATHUN, BRITT · 2019 to 2023
$947k
Sexual Networks and HIV Transmission Clusters among Substance Using MSMK01DA040543 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PINES, HEATHER ALISA · 2015 to 2019
$901k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214NIAID NIH HHS R01 AI135992NIDA NIH HHS K01 DA040543NIDA NIH HHS K01 DA049665NIDA NIH HHS R01 DA037811
6 · The paper itself

Abstract

OBJECTIVE To characterize recent HIV infections among newly diagnosed men who have sex with men and transgender women in Tijuana. METHODS Limiting Antigen (LAg)-Avidity testing was performed to detect recent HIV infection within a cohort of newly-diagnosed men who have sex with men and transgender women in Tijuana. Logistic regression was used to determine characteristics associated with recent infection. A partial transmission network was inferred using HIV-1 pol sequences. Tamura-Nei 93 genetic distances were measured between all pairs of sequences, and the network was constructed by inferring putative transmission links (genetic distances ≤ 1.5%). We assessed whether recent infection was associated with clustering within the inferred network. RESULTS Recent infection was detected in 11% (22/194) of newly-diagnosed participants. Out of the participants with sequence data, 60% (9/15) with recent infection clustered compared with 31% (43/139) with chronic infection. Two recent infections belonged to the same cluster. In adjusted analyses, recent infection was associated with years of residence in Tijuana (OR = 1.5; 95%CI 1.01-1.09), cocaine use (past month) (OR = 8.50; 95%CI 1.99-28.17), and ever experiencing sexual abuse (OR = 2.85; 95%CI 1.03-7.85). DISCUSSION A total of 11% of men newly diagnosed with HIV who have sex with men and transgender women in Tijuana were recently infected. The general lack of clustering between participants with recent infection suggests continued onward HIV transmission rather than an outbreak within a particular cluster.

Indexed as

Homosexuality, MaleTransgender PersonsBrazilFemaleHIV InfectionsHumansMaleSubstance-Related Disorders

Identifiers

PMID32876301
PMCPMC7446761
OpenAlexW3082724178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.