ArticleeLife2020
Structural analysis of the
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 74 citations in OpenAlex.
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- Reprogramming host histone modifications by bacterial pathogens.Molecules and cells · 2026Review
- Type IV Secretion System Drives Lipid Mixing.bioRxiv : the preprint server for biology · 2026Article
- Type IV secretion systems: reconciling diversity through a unified nomenclature.FEMS microbiology reviews · 2026Review
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- Transmembrane effector substrates of type IV secretion systems: mechanisms of secretion and insertion into host cell membranes.microLife · 2026Review
- Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026Review
- Structural and functional insights into Pseudomonas aeruginosa's secretion systems 1-6: regulation, role in microbial keratitis and drug targets.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Review
- Substrate-enhanced filamentation of 3-methylcrotonyl-CoA carboxylase inbioRxiv : the preprint server for biology · 2025Article
- Conformational transitions enabling interkingdom transfer of effector multitudes.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Type IV secretion systems: from structures to mechanisms.The EMBO journal · 2025Review
- The Legionella pneumophila Dot/Icm Type IV Secretion System is Structurally and Functionally Resilient in Absence of Species-specific Proteins Dis2 and Dis3.Journal of molecular biology · 2025Article
- In situ structures of theProceedings of the National Academy of Sciences of the United States of America · 2025Article
- SOLeNNoID: a deep learning pipeline for solenoid residue detection in protein structures.Bioinformatics (Oxford, England) · 2025Article
- OptimizedMicrobiology spectrum · 2025Article
- Review
- A comprehensive two-hybrid analysis to explore themSystems · 2024Article
- The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors.PLoS pathogens · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Clarissa L Durie *Life Sciences Institute, University of Michigan, Ann Arbor, United States.ORCID 0000-0002-4027-4386
Michael J Sheedlo *Department of Pathology, Microbiology, and Immunology, Department of Pathology, Vanderbilt University Medical Center, Nashville, United States.ORCID 0000-0002-3185-1727
Jeong Min ChungLife Sciences Institute, University of Michigan, Ann Arbor, United States.ORCID 0000-0002-4285-8764
Brenda G ByrneDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, United States.
Min SuLife Sciences Institute, University of Michigan, Ann Arbor, United States.
Thomas KnightDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, United States.
Michele SwansonDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, United States.ORCID 0000-0003-2542-0266
D Borden LacyDepartment of Pathology, Microbiology, and Immunology, Department of Pathology, Vanderbilt University Medical Center, Nashville, United States.ORCID 0000-0003-2273-8121
Melanie D OhiLife Sciences Institute, University of Michigan, Ann Arbor, United States.ORCID 0000-0003-1750-4793
University of Michigan · USVanderbilt University Medical Center · US
Funding
NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9MZWITTERION SURFACTANT DDMAB FOR IMPROV STABIL OF PROTEINP41RR001209 · NCRR · STANFORD UNIVERSITY · PI SCOTT, EMILY E · 1985 to 2011
$38.9MTRD #3: An automated and streamlined pipeline for in-situ molecular microscopyP41GM103310 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI KIEFT, JEFFREY S · 2012 to 2021
$14.7MTRAINING IN GASTROENTEROLOGYT32DK007673 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 1992 to 2026
$8.4MResource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2MType IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7MCompute Cluster for in vitro and in situ Analysis of Molecular MachinesS10OD030275 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OHI, MELANIE DIANE · 2021 to 2021
$600kSilicon Mechanics Compute ClusterS10OD020011 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SKINIOTIS, GEORGIOS · 2015 to 2015
$490kExploring protein translocation by the Legionella pneumophila Dot/Icm Type IV Section SystemR21AI164651 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OHI, MELANIE DIANE · 2021 to 2022
$429kStructural and functional studies of the Legionella pneumophila dot T4SSF32AI150027 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DURIE, CLARISSA LYNN · 2020 to 2021
$131kNCRR NIH HHS P41 RR001209NIAID NIH HHS F32 AI150027NIAID NIH HHS R01 AI118932NIAID NIH HHS R21 AI164651NIDDK NIH HHS T32 DK007673NIGMS NIH HHS P41 GM103310NIGMS NIH HHS P41 GM103311NIGMS NIH HHS U24 GM129539NIH HHS S10 OD020011NIH HHS S10 OD030275
Abstract
PubMed holds no abstract for this paper.
Indexed as
Bacterial ProteinsCryoelectron MicroscopyLegionella pneumophilaProtein ConformationType IV Secretion SystemsBacterial ProteinsType IV Secretion Systemscryo-EMinfectious diseaseLegionella pneumophilamicrobiologymolecular biophysicspathogenesisstructural biologyType IV Secretion System
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.