Evidence map›Paper›PMID 32875944›Full record

ReviewJournal of biological rhythms2021

Accounting for Time: Circadian Rhythms in the Time of COVID-19.

Shaon Sengupta, Thomas G Brooks, Gregory R Grant, Garret A FitzGerald

Abstract readReview
In one paragraph

Review in Journal of biological rhythms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Review
  10. Journal of personalized medicine · 2021
    Article
  11. Circadian disruption and human health.The Journal of clinical investigation · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shaon SenguptaDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0001-5237-3835
Thomas G BrooksInstitute of Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-6980-0079
Gregory R GrantInstitute of Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania.
Garret A FitzGeraldInstitute of Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania.

Funding

Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Integrative Training in the Neurocircuitry of Affective DisordersT32MH106442 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI SHELINE, YVETTE I · 2016 to 2020
$1.1M
Role of Circadian Clock in Lung InflammationK08HL132053 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI SENGUPTA, SHAON · 2017 to 2020
$638k
NCATS NIH HHS UL1 TR000003NHLBI NIH HHS K08 HL132053NIMH NIH HHS T32 MH106442
6 · The paper itself

Abstract

The COVID-19 pandemic has necessitated novel approaches and collaborative efforts across multiple disciplines. It is known that various aspects of our physiology and response to pathogens are under tight clock control. However, the assimilation of circadian biology into our clinical and research practices is still evolving. Using a focused review of the literature and original analyses of the UK Biobank, we discuss how circadian biology may inform our diagnostic and therapeutic strategies in this pandemic.

Indexed as

Circadian ClocksCircadian RhythmCOVID-19FemaleHumansMaleModels, BiologicalPandemicsSARS-CoV-2Time FactorschronotherapycircadianCOVID-19immunitytranslational medicinevaccines

Identifiers

PMID32875944
PMCPMC8685580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.