ArticleJournal of the American Heart Association2020
Clinically Meaningful Change in Quality of Life and Associated Factors Among Older Patients With Atrial Fibrillation.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Trial
- Atrial Fibrillation Burden: Assessment, Clinical Significance, and Therapeutic Implications.Life (Basel, Switzerland) · 2026Review
- Sex- and Age-Dependent Outcomes of Cryoablation in Atrial Fibrillation: A 3- and 6-Month Post-Procedural QoL Analysis.Journal of arrhythmia · 2026Article
- Quality of life, care needs and priorities in atrial fibrillation: the impact of number and patterns of comorbidities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The prevalence and burden of chronic kidney disease, patterns of anticoagulation prescribing, and major bleeding risk in older adults with atrial fibrillation.BMC geriatrics · 2025Article
- Association of Atrial Fibrillation Symptom Burden With Social Determinants of Health.JACC. Advances · 2025Article
- Impact of Atrial Fibrillation Type on Quality of Life and Clinical Parameters in Patients with Diabetes Mellitus.Journal of cardiovascular development and disease · 2025Article
- Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.Advances in geriatric medicine and research · 2025Article
- Factors Associated with Quality of Life among People with Atrial Fibrillation: Jordan Atrial Fibrillation Registry Study.Medicina (Kaunas, Lithuania) · 2024Article
- Current Gaps in the Provision of Safe and Effective Anticoagulation in Atrial Fibrillation and the Potential for Factor XI-Directed Therapeutics.Critical pathways in cardiology · 2024Review
- Correlation between family function and quality of life in patients with atrial fibrillation.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Article
- Perception of atrial fibrillation symptoms: Impact on quality of life and treatment in older adults.Journal of the American Geriatrics Society · 2022Article
- Between-group minimally important change versus individual treatment responders.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Review
- Clinically Meaningful Change in Quality of Life and Associated Factors Among Older Patients With Atrial Fibrillation.Journal of the American Heart Association · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Background Among older patients with atrial fibrillation, there are limited data examining clinically meaningful changes in quality of life (QoL). We examined the extent of, and factors associated with, clinically meaningful change in QoL over 1-year among older adults with atrial fibrillation. Methods and Results Patients from cardiology, electrophysiology, and primary care clinics in Massachusetts and Georgia were enrolled in a cohort study (2015-2018). The Atrial Fibrillation Effect on Quality-of-Life questionnaire was used to assess overall QoL and across 3 subscales: symptoms, daily activities, and treatment concern. Clinically meaningful change in QoL (ie, difference between 1-year and baseline QoL score) was categorized as either a decline (≤-5.0 points), no clinically meaningful change (-5.0 to +5.0 points), or an increase (≥+5.0 points). Ordinal logistic models were used to examine factors associated with QoL changes. Participants (n=1097) were on average 75 years old, 48% were women, and 87% White. Approximately 40% experienced a clinically meaningful increase in QoL and 1 in every 5 patients experienced a decline in QoL. After multivariable adjustment, women, non-Whites, those who reported depressive and anxiety symptoms, fair/poor self-rated health, low social support, heart failure, or diabetes mellitus experienced clinically meaningful declines in QoL. Conclusions These findings provide insights to the magnitude of, and factors associated with, clinically meaningful change in QoL among older patients with atrial fibrillation. Assessment of comorbidities and psychosocial factors may help identify patients at high risk for declining QoL and those who require additional surveillance to maximize important clinical and patient-centered outcomes.
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