ArticleAdvanced materials (Deerfield Beach, Fla.)2020
Reduced Graphene Oxide-Encapsulated Microfiber Patterns Enable Controllable Formation of Neuronal-Like Networks.
Article in Advanced materials (Deerfield Beach, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 90 citations in OpenAlex.
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- Peripheral nerve injury repair by electrical stimulation combined with graphene-based scaffolds.Frontiers in bioengineering and biotechnology · 2024Review
- Neuro-bone tissue engineering: emerging mechanisms, potential strategies, and current challenges.Bone research · 2023Review
- Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models.Bioactive materials · 2023Article
- Advances in Biomimetic Nerve Guidance Conduits for Peripheral Nerve Regeneration.Nanomaterials (Basel, Switzerland) · 2023Review
- Conductive fibers for biomedical applications.Bioactive materials · 2023Review
- Electrical charge on ferroelectric nanocomposite membranes enhances SHED neural differentiation.Bioactive materials · 2023Article
- Non-electric bioelectrical analog strategy by a biophysical-driven nano-micro spatial anisotropic scaffold for regulating stem cell niche and tissue regeneration in a neuronal therapy.Bioactive materials · 2023Article
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Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
Scaffold-guided formation of neuronal-like networks, especially under electrical stimulation, can be an appealing avenue toward functional restoration of injured nervous systems. Here, 3D conductive scaffolds are fabricated based on printed microfiber constructs using near-field electrostatic printing (NFEP) and graphene oxide (GO) coating. Various microfiber patterns are obtained from poly(l-lactic acid-co-caprolactone) (PLCL) using NFEP and complexity is achieved via modulating the fiber overlay angles (45°, 60°, 75°, 90°), fiber diameters (15 to 148 µm), and fiber spatial organization (spider web and tubular structure). Upon coating GO onto PLCL microfibers via a layer-by-layer (L-b-L) assembly technique and in situ reduction into reduced GO (rGO), the obtained conductive scaffolds, with 25-50 layers of rGO, demonstrate superior conductivity (≈0.95 S cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.