Evidence map›Paper›PMID 32875594›Full record

ArticleInternational dental journal2020

Health-related quality of life and its associated predictors in patients with oral lichen planus: a cross-sectional study.

Paswach Wiriyakijja, Stephen Porter, Stefano Fedele, Tim Hodgson, Roddy McMillan, Martina Shephard, Richeal Ni Riordain

Abstract read
In one paragraph

Article in International dental journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paswach WiriyakijjaUCL Eastman Dental Institute, London, UK.
Stephen PorterUCL Eastman Dental Institute, London, UK.
Stefano FedeleUCL Eastman Dental Institute, London, UK.
Tim HodgsonRoyal National ENT & Eastman Dental Hospitals, UCLH Foundation NHS Trust London, London, UK.
Roddy McMillanRoyal National ENT & Eastman Dental Hospitals, UCLH Foundation NHS Trust London, London, UK.
Martina ShephardRoyal National ENT & Eastman Dental Hospitals, UCLH Foundation NHS Trust London, London, UK.
Richeal Ni RiordainUCL Eastman Dental Institute, London, UK.

Funding

Faculty of Dentistry, Chulalongkorn UniversityThe NIHR Clinical Research Network PortfolioThe NIHR University College London Hospitals Biomedical Research Centre
6 · The paper itself

Abstract

objectivesTo investigate levels of quality of life (QoL) and determine associated predictors in patients with oral lichen planus (OLP). MATERIALS AND

methodsA total of 300 patients with OLP at one tertiary Oral Medicine clinic in the UK were recruited in a cross-sectional study from January 2018 to July 2019. The 15-item Chronic Oral Mucosal Disease Questionnaire (COMDQ-15) and 14-item Oral Health Impact Profile (OHIP-14) were used to assess the level of QoL related to OLP. A number of potential determinants were considered, including patient demographics, treatment, the severity of oral symptoms, the clinical activity of the disease, and the patient psychological status, which were measured using the pain-Numerical Rating Scale, the Oral Disease Severity Score, the Hospital Anxiety and Depression Scale, and the 10-item Perceived Stress Scale. Multivariate linear regression was employed to identify independent determinants associated with overall and aspects of QoL.

resultsOn multivariate analyses, after adjusting for confounding variables, the QoL levels in patients with OLP were significantly associated with levels of oral pain, anxiety, stress and use of topical corticosteroids. The COMDQ-15 instrument performed better than OHIP-14 at capturing the association between QoL and pain and disease activity in patients with OLP.

conclusionClinicians should expect reduced QoL in OLP patients with high pain levels, high anxiety levels, high perceived stress and use of topical corticosteroids. The COMDQ-15 is best suited to measure QoL in this population.

Indexed as

Chronic Oral Mucosal Disease QuestionnaireOral lichen planusquality of life

Identifiers

PMID32875594
PMCPMC9275316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.