Evidence map›Paper›PMID 32875482›Full record

ArticleDemography2020

Brazil's Missing Infants: Zika Risk Changes Reproductive Behavior.

Marcos A Rangel, Jenna Nobles, Amar Hamoudi

Open access · bronzeAbstract read
In one paragraph

Article in Demography, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Childbearing attitudes amid successive novel infectious disease epidemics: a mixed-method experimental approach.Social forces; a scientific medium of social study and interpretation · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Fertility in a Pandemic: Evidence from California.Population and development review · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marcos A RangelSanford School of Public Policy, Duke University, 302 Towerview Road, Rubenstein Hall, Office 262, Durham, NC, 27708, USA. marcos.rangel@duke.edu.
Jenna NoblesDepartment of Sociology, University of Wisconsin-Madison, Madison, WI, USA.
Amar HamoudiCenter for Demography and Ecology, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · USDuke University · US

Funding

Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI James Moody · 2015 to 2026
$5.7M
Scientific and Technical CoreP2CHD047873 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine J. Curtis · 2014 to 2026
$5.1M
Fecundity and Fertility in the Presence of ZikaR03HD092818 · NICHD · DUKE UNIVERSITY · PI DE ALMEIDA RANGEL, MARCOS · 2017 to 2018
$171k
NICHD NIH HHS P2C HD047873NICHD NIH HHS P2C HD065563NICHD NIH HHS R03 HD092818
6 · The paper itself

Abstract

Zika virus epidemics have potential large-scale population effects. Controlled studies of mice and nonhuman primates indicate that Zika affects fecundity, raising concerns about miscarriage in human populations. In regions of Brazil, Zika risk peaked months before residents learned about the epidemic and its relation to congenital anomalies. This spatiotemporal variation supports analysis of both biological effects of Zika infection on fertility and the effects of learning about Zika risk on reproductive behavior. Causal inference techniques used with vital statistics indicate that the epidemic caused reductions in birth cohort size of approximately one-quarter 18 months after Zika infection risk peaked but 10 months after public health messages advocated childbearing delay. The evidence is consistent with small but not statistically detectable biological reductions in fecundity, as well as large strategic changes in reproductive behavior to temporally align childbearing with reduced risk to infant health. The behavioral effects are larger for more-educated and older women, which may reflect facilitated access to information and to family planning services within high-risk, mosquito-infested urban locations as well as perceptions about the opportunity costs of risks to pregnancy and infant survival.

Indexed as

AdultAge FactorsBrazilEpidemicsFemaleHumansMicrocephalyPregnancyPregnancy Complications, InfectiousReproductive BehaviorResidence CharacteristicsSocioeconomic FactorsYoung AdultZika Virus InfectionAvoidanceFecundityFertilityTempo effectsZika

Identifiers

PMID32875482
PMCPMC7606566
OpenAlexW3081840470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.