Evidence map›Paper›PMID 32875390›Full record

ArticleEuropean radiology experimental2020

2D perfusion DSA with an open-source, semi-automated, color-coded software for the quantification of foot perfusion following infrapopliteal angioplasty: a feasibility study.

George C Kagadis, Stavros Tsantis, Ilias Gatos, Stavros Spiliopoulos, Konstantinos Katsanos, Dimitris Karnabatidis

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In one paragraph

Article in European radiology experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04356092 (Feasibility of 2D Perfusion DSA With Custom-made, Color-coded Software for the Quantification of Foot Perfusion Following Infrapopliteal Angioplasty), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04356092 nacompletednot on this map

Feasibility of 2D Perfusion DSA With Custom-made, Color-coded Software for the Quantification of Foot Perfusion Following Infrapopliteal Angioplasty

TypeinterventionalSponsorAttikon HospitalRan2017 to 2019Enrolled7ConditionsIschemia LimbArms2D perfusion digital subtraction angiography of the foot.
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George C KagadisDepartment of Medical Physics, School of Medicine, University of Patras, GR 26504, Rion, Greece.
Stavros TsantisDepartment of Medical Physics, School of Medicine, University of Patras, GR 26504, Rion, Greece.
Ilias GatosDepartment of Medical Physics, School of Medicine, University of Patras, GR 26504, Rion, Greece.
Stavros Spiliopoulos2nd Department of Radiology, School of Medicine, "ATTIKON" University Hospital, National and Kapodistrian University of Athens, GR 12461, Athens, Greece. stavspiliop@med.uoa.gr.ORCID 0000-0003-1860-0568
Konstantinos KatsanosDepartment of Radiology, School of Medicine, University of Patras, GR 26504, Rion, Greece.
Dimitris KarnabatidisDepartment of Radiology, School of Medicine, University of Patras, GR 26504, Rion, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFoot perfusion has been recently implemented as a new tool for optimizing outcomes of peripheral endovascular procedures. A custom-made, two-dimensional perfusion digital subtraction angiography (PDSA) algorithm has been implemented to quantify outcomes of endovascular treatment of critical limb ischemia (CLI), assist intra-procedural decision-making, and enhance clinical outcomes.

methodsThe study was approved by the Hospital's Ethics Committee. This prospective, single-center study included seven consecutive patients scheduled to undergo infrapopliteal endovascular treatment of CLI. Perfusion blood volume (PBV), mean transit time (MTT), and perfusion blood flow (PBF) maps were extracted by analyzing time-intensity curves and signal intensity on the perfused vessel mask. Mean values calculated from user-specified regions of interest (ROIs) on perfusion maps were employed to evaluate pre- and post-endovascular treatment condition. Measurements were performed immediately after final PDSA.

resultsIn total, five patients (aged 54 ± 16 years, mean ± standard deviation) were analyzed, as two patients were excluded due to significant motion artifacts. Post-procedural MTT presented a mean decrease of 19.1% for all patients and increased only in 1 of 5 patients, demonstrating in 4/5 patients an increase in tissue perfusion after revascularization. Overall mean PBF and PBV values were also analogously increased following revascularization (446% and 69.5% mean, respectively) and in the majority of selected ROIs (13/15 and 12/15 ROIs, respectively).

conclusionsQuantification of infrapopliteal angioplasty outcomes using this newly proposed, custom-made, intra-procedural PDSA algorithm was performed using PBV, MTT, and PBF maps. Further studies are required to determine its role in peripheral endovascular procedures ( ClinicalTrials.gov Identifier: NCT04356092).

Indexed as

Angiography, Digital SubtractionSoftwareAlgorithmsBlood Flow VelocityEndovascular ProceduresFeasibility StudiesFemaleFootHumansIschemiaMaleMiddle AgedPeripheral Arterial DiseaseProspective StudiesRadiographic Image Interpretation, Computer-AssistedAngiography (digital subtraction)Endovascular proceduresFootPerfusionPeripheral arterial disease

Identifiers

PMID32875390
PMCPMC7462946

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Registered trials

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