Evidence map›Paper›PMID 32875377›Full record

ArticleInternational journal of colorectal disease2021

Colonic diverticular disease in autosomal dominant polycystic kidney disease: is there really an association? A nationwide analysis.

Rodrigo Duarte-Chavez, Jill Stoltzfus, Vikas Yellapu, Noel Martins, Sudip Nanda, Santo Longo, Berhanu Geme, Yecheskel Schneider

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rodrigo Duarte-ChavezDepartment of Internal Medicine, Division of Gastroenterology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA. rodrigo.duartechavez@sluhn.org.ORCID http://orcid.org/0000-0001-8134-4072
Jill StoltzfusDepartment of Research, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Vikas YellapuDepartment of Research, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Noel MartinsDepartment of Internal Medicine, Division of Gastroenterology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Sudip NandaDepartment of Internal Medicine, Division of Cardiology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Santo LongoDepartment of Pathology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Berhanu GemeDepartment of Internal Medicine, Division of Gastroenterology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
Yecheskel SchneiderDepartment of Internal Medicine, Division of Gastroenterology, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA.
St. Luke's University Health Network · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeColonic diverticulosis, diverticulitis, and diverticular bleeding are reportedly more common in patients with autosomal dominant polycystic kidney disease (ADPKD). Other studies have questioned this association. The objectives of our study are to clarify this association using a larger patient population and to identify risk factors in general to develop diverticular disease.

methodsThe Nationwide Inpatient Sample weighted discharges from 2003 to 2011 were used to assess for the prevalence of diverticular disease in the population with ADPKD compared with the general population without ADPKD. A multivariable direct logistic regression model was constructed to determine independent predictors of diverticular disease in the general population.

resultsThe prevalence of diverticulosis, diverticulitis, and diverticular bleeding were considerably increased in patients with ADPKD compared with the general population without ADPKD. The prevalence of colonic surgery was less in ADPKD patients with diverticulitis. In patients with kidney transplant, the prevalence of diverticulitis was increased in the ADPKD group, but colonic surgery was not significantly different between both groups. The prevalence of diverticular bleeding was slightly elevated in patients with ADPKD, but colonic surgery was significantly increased in patients with ADPKD. NSAID use, hypertension, constipation, and ADPKD had increased odds ratios for diverticular disease during multivariate analysis.

conclusionThere is an increased prevalence of colonic diverticular disease in the population with ADPKD.

Indexed as

Diverticular DiseasesDiverticulitisDiverticulosis, ColonicKidney TransplantationPolycystic Kidney, Autosomal DominantHumansRisk FactorsAutosomal dominant polycystic kidney diseaseDiverticular bleedingDiverticulitisDiverticulosisNationwide Inpatient Sample

Identifiers

PMID32875377
OpenAlexW3081638541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.