Evidence map›Paper›PMID 32875372›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2020

Cone-beam computed tomography-based radiomics in prostate cancer: a mono-institutional study.

Davide Giovanni Bosetti, Lorenzo Ruinelli, Maria Antonietta Piliero, Linda Christina van der Gaag, Gianfranco Angelo Pesce, Mariacarla Valli, Marco Bosetti, Stefano Presilla, Antonella Richetti, Letizia Deantonio

Abstract read
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  11. Longitudinal stability of HyperSightScientific reports · 2025
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  18. Prostate Cancer Radiogenomics-From Imaging to Molecular Characterization.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Davide Giovanni BosettiRadiation Oncology Clinic, Oncology Institute of Southern Switzerland, Via Gallino, 6500, Bellinzona, Switzerland. davidegiovanni.bosetti@eoc.ch.ORCID http://orcid.org/0000-0002-2654-1281
Lorenzo RuinelliInformation and Communications Technology, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Maria Antonietta PilieroMedical Physics, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland.
Linda Christina van der GaagDalle Molle Institute for Artificial Intelligence Research, Lugano, Switzerland.
Gianfranco Angelo PesceRadiation Oncology Clinic, Oncology Institute of Southern Switzerland, Via Gallino, 6500, Bellinzona, Switzerland.
Mariacarla ValliRadiation Oncology Clinic, Oncology Institute of Southern Switzerland, Via Gallino, 6500, Bellinzona, Switzerland.
Marco BosettiInformation and Communications Technology, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Stefano PresillaMedical Physics, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland.
Antonella RichettiRadiation Oncology Clinic, Oncology Institute of Southern Switzerland, Via Gallino, 6500, Bellinzona, Switzerland.
Letizia DeantonioRadiation Oncology Clinic, Oncology Institute of Southern Switzerland, Via Gallino, 6500, Bellinzona, Switzerland.
Institute of Oncology Research · CHEnte Ospedaliero Cantonale · CHDalle Molle Institute for Artificial Intelligence Research · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of the reported study was to investigate the value of cone-beam computed tomography (CBCT)-based radiomics for risk stratification and prediction of biochemical relapse in prostate cancer.

methodsThe study population consisted of 31 prostate cancer patients. Radiomics features were extracted from weekly CBCT scans performed for verifying treatment position. From the data, logistic-regression models were learned for establishing tumor stage, Gleason score, level of prostate-specific antigen, and risk stratification, and for predicting biochemical recurrence. Performance of the learned models was assessed using the area under the receiver operating characteristic curve (AUC-ROC) or the area under the precision-recall curve (AUC-PRC).

resultsResults suggest that the histogram-based Energy and Kurtosis features and the shape-based feature representing the standard deviation of the maximum diameter of the prostate gland during treatment are predictive of biochemical relapse and indicative of patients at high risk.

conclusionOur results suggest the usefulness of CBCT-based radiomics for treatment definition in prostate cancer.

Indexed as

Computational BiologyMachine LearningRadiotherapy, Intensity-ModulatedAdenocarcinomaAgedAged, 80 and overArea Under CurveCone-Beam Computed TomographyHumansImage Processing, Computer-AssistedLogistic ModelsMaleMiddle AgedNeoplasm GradingNeoplasm StagingProstate-Specific AntigenProstate-Specific AntigenBiochemical recurrenceCone-beam computed tomographyProstate cancerRadiomicsRadiotherapy

Identifiers

PMID32875372
OpenAlexW3082797904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.